Parent Directory| Name | Size | Last Modified |
|---|---|---|
 0000874015-25-000089-index-headers.html | 2025-02-19 16:06:39 | |
| 0000874015-25-000089-index.html | 2025-02-19 16:06:39 | |
| 0000874015-25-000089.txt | 2025-02-19 16:06:39 | |
 0000874015-25-000089-xbrl.zip | 921447 | 2025-02-19 16:06:39 |
| exhibit10-58.htm | 261830 | 2025-02-19 16:06:39 |
| exhibit19.htm | 30756 | 2025-02-19 16:06:39 |
| exhibit23-1.htm | 4575 | 2025-02-19 16:06:39 |
| exhibit31-1.htm | 12750 | 2025-02-19 16:06:39 |
| exhibit31-2.htm | 12758 | 2025-02-19 16:06:39 |
| exhibit32-1.htm | 7304 | 2025-02-19 16:06:39 |
| FilingSummary.xml | 52345 | 2025-02-19 16:06:39 |
| Financial_Report.xlsx | 185668 | 2025-02-19 16:06:39 |
| form10k.htm | 3510645 | 2025-02-19 16:06:39 |
| form10k_htm.xml | 2733343 | 2025-02-19 16:06:39 |
 image01.jpg | 81780 | 2025-02-19 16:06:39 |
 image02.jpg | 101508 | 2025-02-19 16:06:39 |
 image03.jpg | 111416 | 2025-02-19 16:06:39 |
 image04.jpg | 181472 | 2025-02-19 16:06:39 |
| ions-20241231.xsd | 106956 | 2025-02-19 16:06:39 |
| ions-20241231_cal.xml | 141990 | 2025-02-19 16:06:39 |
| ions-20241231_def.xml | 670666 | 2025-02-19 16:06:39 |
| ions-20241231_lab.xml | 1540596 | 2025-02-19 16:06:39 |
| ions-20241231_pre.xml | 942187 | 2025-02-19 16:06:39 |
| MetaLinks.json | 1189189 | 2025-02-19 16:06:39 |
| R1.htm | 68346 | 2025-02-19 16:06:39 |
| R10.htm | 41534 | 2025-02-19 16:06:39 |
| R11.htm | 53256 | 2025-02-19 16:06:39 |
| R12.htm | 128691 | 2025-02-19 16:06:39 |
| R13.htm | 175590 | 2025-02-19 16:06:39 |
| R14.htm | 53003 | 2025-02-19 16:06:39 |
| R15.htm | 110572 | 2025-02-19 16:06:39 |
| R16.htm | 134955 | 2025-02-19 16:06:39 |
| R17.htm | 163943 | 2025-02-19 16:06:39 |
| R18.htm | 8501 | 2025-02-19 16:06:39 |
| R19.htm | 5698 | 2025-02-19 16:06:39 |
| R2.htm | 111703 | 2025-02-19 16:06:39 |
| R20.htm | 44686 | 2025-02-19 16:06:39 |
| R21.htm | 22540 | 2025-02-19 16:06:39 |
| R22.htm | 54043 | 2025-02-19 16:06:39 |
| R23.htm | 23479 | 2025-02-19 16:06:39 |
| R24.htm | 141162 | 2025-02-19 16:06:39 |
| R25.htm | 8075 | 2025-02-19 16:06:39 |
| R26.htm | 45209 | 2025-02-19 16:06:39 |
| R27.htm | 36162 | 2025-02-19 16:06:39 |
| R28.htm | 69562 | 2025-02-19 16:06:39 |
| R29.htm | 176849 | 2025-02-19 16:06:39 |
| R3.htm | 21186 | 2025-02-19 16:06:39 |
| R30.htm | 48010 | 2025-02-19 16:06:39 |
| R31.htm | 93060 | 2025-02-19 16:06:39 |
| R32.htm | 108273 | 2025-02-19 16:06:39 |
| R33.htm | 163547 | 2025-02-19 16:06:39 |
| R34.htm | 37138 | 2025-02-19 16:06:39 |
| R35.htm | 22145 | 2025-02-19 16:06:39 |
| R36.htm | 5263 | 2025-02-19 16:06:39 |
| R37.htm | 16112 | 2025-02-19 16:06:39 |
| R38.htm | 4604 | 2025-02-19 16:06:39 |
| R39.htm | 4329 | 2025-02-19 16:06:39 |
| R4.htm | 94442 | 2025-02-19 16:06:39 |
| R40.htm | 11354 | 2025-02-19 16:06:39 |
| R41.htm | 51848 | 2025-02-19 16:06:39 |
| R42.htm | 6126 | 2025-02-19 16:06:39 |
| R43.htm | 19098 | 2025-02-19 16:06:39 |
| R44.htm | 13689 | 2025-02-19 16:06:39 |
| R45.htm | 9012 | 2025-02-19 16:06:39 |
| R46.htm | 10553 | 2025-02-19 16:06:39 |
| R47.htm | 23362 | 2025-02-19 16:06:39 |
| R48.htm | 12000 | 2025-02-19 16:06:39 |
| R49.htm | 42937 | 2025-02-19 16:06:39 |
| R5.htm | 25218 | 2025-02-19 16:06:39 |
| R50.htm | 70263 | 2025-02-19 16:06:39 |
| R51.htm | 126665 | 2025-02-19 16:06:39 |
| R52.htm | 35329 | 2025-02-19 16:06:39 |
| R53.htm | 70170 | 2025-02-19 16:06:39 |
| R54.htm | 69640 | 2025-02-19 16:06:39 |
| R55.htm | 47491 | 2025-02-19 16:06:39 |
| R56.htm | 5543 | 2025-02-19 16:06:39 |
| R57.htm | 11795 | 2025-02-19 16:06:39 |
| R58.htm | 10854 | 2025-02-19 16:06:39 |
| R59.htm | 26616 | 2025-02-19 16:06:39 |
| R6.htm | 58912 | 2025-02-19 16:06:39 |
| R60.htm | 16355 | 2025-02-19 16:06:39 |
| R61.htm | 97761 | 2025-02-19 16:06:39 |
| R62.htm | 47069 | 2025-02-19 16:06:39 |
| R63.htm | 93623 | 2025-02-19 16:06:39 |
| R64.htm | 30870 | 2025-02-19 16:06:39 |
| R65.htm | 84750 | 2025-02-19 16:06:39 |
| R66.htm | 51609 | 2025-02-19 16:06:39 |
| R67.htm | 30997 | 2025-02-19 16:06:39 |
| R68.htm | 58283 | 2025-02-19 16:06:39 |
| R69.htm | 27337 | 2025-02-19 16:06:39 |
| R7.htm | 126983 | 2025-02-19 16:06:39 |
| R70.htm | 39394 | 2025-02-19 16:06:39 |
| R71.htm | 44162 | 2025-02-19 16:06:39 |
| R72.htm | 151015 | 2025-02-19 16:06:39 |
| R73.htm | 55701 | 2025-02-19 16:06:39 |
| R74.htm | 32239 | 2025-02-19 16:06:39 |
| R75.htm | 32241 | 2025-02-19 16:06:39 |
| R76.htm | 15647 | 2025-02-19 16:06:39 |
| R77.htm | 29651 | 2025-02-19 16:06:39 |
| R78.htm | 12611 | 2025-02-19 16:06:39 |
| R79.htm | 26861 | 2025-02-19 16:06:39 |
| R8.htm | 8679 | 2025-02-19 16:06:39 |
| R80.htm | 78773 | 2025-02-19 16:06:39 |
| R81.htm | 37870 | 2025-02-19 16:06:39 |
| R82.htm | 15872 | 2025-02-19 16:06:39 |
| R83.htm | 19591 | 2025-02-19 16:06:39 |
| R84.htm | 10069 | 2025-02-19 16:06:39 |
| R85.htm | 48332 | 2025-02-19 16:06:39 |
| R86.htm | 54366 | 2025-02-19 16:06:39 |
| R9.htm | 79712 | 2025-02-19 16:06:39 |
| report.css | 2768 | 2025-02-19 16:06:39 |
| Show.js | 1086 | 2025-02-19 16:06:39 |