CONSOLIDATED BALANCE SHEETS - USD ($) $ in Thousands	Dec. 31, 2024	Dec. 31, 2023
Current assets:
Cash and cash equivalents	$ 242,077	$ 399,266
Short-term investments	2,055,579	1,931,935
Contracts receivable	92,188	97,778
Inventories	12,512	7,441
Other current assets	217,934	205,433
Total current assets	2,620,290	2,641,853
Property, plant and equipment, net	94,251	71,043
Right-of-use assets	161,856	171,896
Deposits and other assets	127,278	105,280
Total assets	3,003,675	2,990,072
Current liabilities:
Accounts payable	42,964	26,027
Accrued compensation	69,614	67,727
Accrued liabilities	108,438	147,894
Income taxes payable	34	2,151
0.125 percent convertible senior notes, net	0	44,332
Current portion of deferred contract revenue	78,989	151,128
Other current liabilities	9,279	8,831
Total current liabilities	309,318	448,090
Long-term deferred contract revenue	156,504	241,184
Liability related to sale of future royalties, net	542,212	513,736
Long-term lease liabilities	161,805	170,875
Long-term obligations	51,924	41,836
Total liabilities	2,415,324	2,603,386
Stockholders' equity:
Common stock, $0.001 par value; 300,000,000 shares authorized, 157,908,815 and 144,340,526 shares issued and outstanding at December 31, 2024 and December 31, 2023, respectively	158	144
Additional paid-in capital	2,868,812	2,215,098
Accumulated other comprehensive loss	(30,811)	(32,645)
Accumulated deficit	(2,249,808)	(1,795,911)
Total stockholders' equity	588,351	386,686
Total liabilities and stockholders' equity	3,003,675	2,990,072
1.75 Percent Convertible Senior Notes [Member]
Current liabilities:
Convertible senior notes, net	565,026	562,285
0 Percent Convertible Senior Notes [Member]
Current liabilities:
Convertible senior notes, net	$ 628,535	$ 625,380