Supplemental Financial Data, Accrued Liabilities (Details) - USD ($) $ in Thousands	Dec. 31, 2024	Dec. 31, 2023
Accrued Liabilities [Abstract]
Clinical expenses	$ 77,436	$ 105,967
In-licensing expenses	7,951	7,454
Commercial expenses	3,589	4,875
Other miscellaneous expenses	19,462	29,598
Total accrued liabilities	$ 108,438	$ 147,894