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| 0000874015-22-000104.txt | 2022-05-04 17:11:19 | |
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| ex10-1.htm | 145789 | 2022-05-04 17:11:19 |
| ex31_1.htm | 13444 | 2022-05-04 17:11:19 |
| ex31_2.htm | 13309 | 2022-05-04 17:11:19 |
| ex32_1.htm | 7338 | 2022-05-04 17:11:19 |
| FilingSummary.xml | 23195 | 2022-05-04 17:11:19 |
| Financial_Report.xlsx | 81496 | 2022-05-04 17:11:19 |
| form10q.htm | 1648222 | 2022-05-04 17:11:19 |
| form10q_htm.xml | 1310615 | 2022-05-04 17:11:19 |
| ions-20220331.xsd | 42690 | 2022-05-04 17:11:19 |
| ions-20220331_cal.xml | 61287 | 2022-05-04 17:11:19 |
| ions-20220331_def.xml | 253270 | 2022-05-04 17:11:19 |
| ions-20220331_lab.xml | 702725 | 2022-05-04 17:11:19 |
| ions-20220331_pre.xml | 361749 | 2022-05-04 17:11:19 |
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| R10.htm | 166206 | 2022-05-04 17:11:19 |
| R11.htm | 70653 | 2022-05-04 17:11:19 |
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| R18.htm | 167503 | 2022-05-04 17:11:19 |
| R19.htm | 67438 | 2022-05-04 17:11:19 |
| R2.htm | 106073 | 2022-05-04 17:11:19 |
| R20.htm | 14848 | 2022-05-04 17:11:19 |
| R21.htm | 22913 | 2022-05-04 17:11:19 |
| R22.htm | 45143 | 2022-05-04 17:11:19 |
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| R27.htm | 6988 | 2022-05-04 17:11:19 |
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| R29.htm | 11863 | 2022-05-04 17:11:19 |
| R3.htm | 17974 | 2022-05-04 17:11:19 |
| R30.htm | 4975 | 2022-05-04 17:11:19 |
| R31.htm | 83131 | 2022-05-04 17:11:19 |
| R32.htm | 16522 | 2022-05-04 17:11:19 |
| R33.htm | 91450 | 2022-05-04 17:11:19 |
| R34.htm | 48148 | 2022-05-04 17:11:19 |
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| report.css | 2767 | 2022-05-04 17:11:19 |
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