Significant Accounting Policies, Cash, Cash Equivalents and Investments (Details) $ in Thousands	3 Months Ended		12 Months Ended
	Mar. 31, 2022 USD ($) Company	Mar. 31, 2021 USD ($)	Dec. 31, 2020 USD ($) Investment
Cash, Cash Equivalents and Investments [Abstract]
Number of publicly held companies in which there is an equity ownership interest of less than 20% | Company	3
Number of privately held companies in which there is an equity ownership interest of less than 20% | Company	7
Number of investments in privately held companies that were revalued | Investment			3
Gain on investments | $	$ (6,625)	$ 0
Investments in Dynacure, Suzhou-Ribo and Aro Biotherapeutics [Member]
Cash, Cash Equivalents and Investments [Abstract]
Gain on investments | $			$ 14,800