Parent Directory| Name | Size | Last Modified |
|---|---|---|
 0000874015-26-000177-index-headers.html | 2026-04-29 14:33:38 | |
| 0000874015-26-000177-index.html | 2026-04-29 14:33:38 | |
| 0000874015-26-000177.txt | 2026-04-29 14:33:38 | |
 0000874015-26-000177-xbrl.zip | 207039 | 2026-04-29 14:33:38 |
| ex10-1.htm | 22414 | 2026-04-29 14:33:38 |
| ex10-2.htm | 10226 | 2026-04-29 14:33:38 |
| ex31-1.htm | 8512 | 2026-04-29 14:33:38 |
| ex31-2.htm | 8439 | 2026-04-29 14:33:38 |
| ex32-1.htm | 4870 | 2026-04-29 14:33:38 |
| FilingSummary.xml | 37046 | 2026-04-29 14:33:38 |
| form10q.htm | 1064154 | 2026-04-29 14:33:38 |
| form10q_htm.xml | 806372 | 2026-04-29 14:33:38 |
| ions-20260331.xsd | 58163 | 2026-04-29 14:33:38 |
| ions-20260331_cal.xml | 71745 | 2026-04-29 14:33:38 |
| ions-20260331_def.xml | 315489 | 2026-04-29 14:33:38 |
| ions-20260331_lab.xml | 512721 | 2026-04-29 14:33:38 |
| ions-20260331_pre.xml | 343766 | 2026-04-29 14:33:38 |
| MetaLinks.json | 870524 | 2026-04-29 14:33:38 |
| R1.htm | 51781 | 2026-04-29 14:33:38 |
| R10.htm | 7553 | 2026-04-29 14:33:38 |
| R11.htm | 21040 | 2026-04-29 14:33:38 |
| R12.htm | 34067 | 2026-04-29 14:33:38 |
| R13.htm | 25564 | 2026-04-29 14:33:38 |
| R14.htm | 9579 | 2026-04-29 14:33:38 |
| R15.htm | 90695 | 2026-04-29 14:33:38 |
| R16.htm | 34503 | 2026-04-29 14:33:38 |
| R17.htm | 27195 | 2026-04-29 14:33:38 |
| R18.htm | 11923 | 2026-04-29 14:33:38 |
| R19.htm | 35966 | 2026-04-29 14:33:38 |
| R2.htm | 119502 | 2026-04-29 14:33:38 |
| R20.htm | 5836 | 2026-04-29 14:33:38 |
| R21.htm | 22564 | 2026-04-29 14:33:38 |
| R22.htm | 17742 | 2026-04-29 14:33:38 |
| R23.htm | 39149 | 2026-04-29 14:33:38 |
| R24.htm | 34343 | 2026-04-29 14:33:38 |
| R25.htm | 21770 | 2026-04-29 14:33:38 |
| R26.htm | 19066 | 2026-04-29 14:33:38 |
| R27.htm | 22141 | 2026-04-29 14:33:38 |
| R28.htm | 92612 | 2026-04-29 14:33:38 |
| R29.htm | 28606 | 2026-04-29 14:33:38 |
| R3.htm | 17550 | 2026-04-29 14:33:38 |
| R30.htm | 26547 | 2026-04-29 14:33:38 |
| R31.htm | 8184 | 2026-04-29 14:33:38 |
| R32.htm | 28241 | 2026-04-29 14:33:38 |
| R33.htm | 15259 | 2026-04-29 14:33:38 |
| R34.htm | 5190 | 2026-04-29 14:33:38 |
| R35.htm | 16369 | 2026-04-29 14:33:38 |
| R36.htm | 11982 | 2026-04-29 14:33:38 |
| R37.htm | 23998 | 2026-04-29 14:33:38 |
| R38.htm | 31901 | 2026-04-29 14:33:38 |
| R39.htm | 22835 | 2026-04-29 14:33:38 |
| R4.htm | 102670 | 2026-04-29 14:33:38 |
| R40.htm | 16945 | 2026-04-29 14:33:38 |
| R41.htm | 24677 | 2026-04-29 14:33:38 |
| R42.htm | 16931 | 2026-04-29 14:33:38 |
| R43.htm | 27756 | 2026-04-29 14:33:38 |
| R44.htm | 16927 | 2026-04-29 14:33:38 |
| R45.htm | 13069 | 2026-04-29 14:33:38 |
| R46.htm | 13604 | 2026-04-29 14:33:38 |
| R47.htm | 14433 | 2026-04-29 14:33:38 |
| R48.htm | 93796 | 2026-04-29 14:33:38 |
| R49.htm | 39979 | 2026-04-29 14:33:38 |
| R5.htm | 28320 | 2026-04-29 14:33:38 |
| R50.htm | 24125 | 2026-04-29 14:33:38 |
| R51.htm | 60471 | 2026-04-29 14:33:38 |
| R52.htm | 48901 | 2026-04-29 14:33:38 |
| R53.htm | 16229 | 2026-04-29 14:33:38 |
| R54.htm | 21790 | 2026-04-29 14:33:38 |
| R55.htm | 20733 | 2026-04-29 14:33:38 |
| R56.htm | 26414 | 2026-04-29 14:33:38 |
| R57.htm | 16169 | 2026-04-29 14:33:38 |
| R58.htm | 52171 | 2026-04-29 14:33:38 |
| R59.htm | 29825 | 2026-04-29 14:33:38 |
| R6.htm | 44970 | 2026-04-29 14:33:38 |
| R60.htm | 30253 | 2026-04-29 14:33:38 |
| R61.htm | 32648 | 2026-04-29 14:33:38 |
| R62.htm | 7965 | 2026-04-29 14:33:38 |
| R63.htm | 45390 | 2026-04-29 14:33:38 |
| R7.htm | 105075 | 2026-04-29 14:33:38 |
| R8.htm | 4883 | 2026-04-29 14:33:38 |
| R9.htm | 9315 | 2026-04-29 14:33:38 |
| report.css | 2767 | 2026-04-29 14:33:38 |
| Show.js | 1085 | 2026-04-29 14:33:38 |