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|---|---|---|
 0000944809-16-000019-index-headers.html | 2016-03-24 16:16:42 | |
| 0000944809-16-000019-index.html | 2016-03-24 16:16:42 | |
| 0000944809-16-000019.txt | 2016-03-24 16:16:42 | |
 0000944809-16-000019-xbrl.zip | 77262 | 2016-03-24 16:16:42 |
| exhibit233.htm | 7330 | 2016-03-24 16:16:42 |
| exhibit313.htm | 5603 | 2016-03-24 16:16:42 |
| exhibit314.htm | 5614 | 2016-03-24 16:16:42 |
| exhibit323.htm | 4368 | 2016-03-24 16:16:42 |
| exhibit324.htm | 4613 | 2016-03-24 16:16:42 |
| FilingSummary.xml | 9496 | 2016-03-24 16:16:42 |
| Financial_Report.xlsx | 25209 | 2016-03-24 16:16:42 |
| opk-20151231.xml | 253618 | 2016-03-24 16:16:42 |
| opk-20151231.xsd | 17467 | 2016-03-24 16:16:42 |
| opk-20151231_cal.xml | 43679 | 2016-03-24 16:16:42 |
| opk-20151231_def.xml | 133679 | 2016-03-24 16:16:42 |
| opk-20151231_lab.xml | 274368 | 2016-03-24 16:16:42 |
| opk-20151231_pre.xml | 158269 | 2016-03-24 16:16:42 |
| opk1231201510-ka.htm | 494184 | 2016-03-24 16:16:42 |
| R1.htm | 30219 | 2016-03-24 16:16:42 |
| R10.htm | 6047 | 2016-03-24 16:16:42 |
| R11.htm | 5722 | 2016-03-24 16:16:42 |
| R12.htm | 6689 | 2016-03-24 16:16:42 |
| R13.htm | 49648 | 2016-03-24 16:16:42 |
| R14.htm | 15772 | 2016-03-24 16:16:42 |
| R15.htm | 84805 | 2016-03-24 16:16:42 |
| R16.htm | 25759 | 2016-03-24 16:16:42 |
| R2.htm | 56408 | 2016-03-24 16:16:42 |
| R3.htm | 10791 | 2016-03-24 16:16:42 |
| R4.htm | 51471 | 2016-03-24 16:16:42 |
| R5.htm | 22219 | 2016-03-24 16:16:42 |
| R6.htm | 115198 | 2016-03-24 16:16:42 |
| R7.htm | 6002 | 2016-03-24 16:16:42 |
| R8.htm | 8519 | 2016-03-24 16:16:42 |
| R9.htm | 62390 | 2016-03-24 16:16:42 |
| report.css | 2767 | 2016-03-24 16:16:42 |
| Show.js | 1410 | 2016-03-24 16:16:42 |