Parent Directory| Name | Size | Last Modified |
|---|---|---|
 0001104659-13-081234-index-headers.html | 2013-11-05 17:29:27 | |
| 0001104659-13-081234-index.html | 2013-11-05 17:29:27 | |
| 0001104659-13-081234.txt | 2013-11-05 17:29:27 | |
 0001104659-13-081234-xbrl.zip | 274927 | 2013-11-05 17:29:27 |
| a13-19600_110q.htm | 1164467 | 2013-11-05 17:29:27 |
| a13-19600_1ex10d1.htm | 1094349 | 2013-11-05 17:29:27 |
| a13-19600_1ex10d2.htm | 80559 | 2013-11-05 17:29:27 |
| a13-19600_1ex10d3.htm | 54165 | 2013-11-05 17:29:27 |
| a13-19600_1ex10d4.htm | 126077 | 2013-11-05 17:29:27 |
| a13-19600_1ex31d1.htm | 9634 | 2013-11-05 17:29:27 |
| a13-19600_1ex31d2.htm | 9662 | 2013-11-05 17:29:27 |
| a13-19600_1ex32d1.htm | 7320 | 2013-11-05 17:29:27 |
| FilingSummary.xml | 19789 | 2013-11-05 17:29:27 |
| Financial_Report.xls | 1463502 | 2013-11-05 17:29:27 |
| Financial_Report.xlsx | 162320 | 2013-11-05 17:29:27 |
| isis-20130930.xml | 1510544 | 2013-11-05 17:29:27 |
| isis-20130930.xsd | 98825 | 2013-11-05 17:29:27 |
| isis-20130930_cal.xml | 48432 | 2013-11-05 17:29:27 |
| isis-20130930_def.xml | 505290 | 2013-11-05 17:29:27 |
| isis-20130930_lab.xml | 1736595 | 2013-11-05 17:29:27 |
| isis-20130930_pre.xml | 771141 | 2013-11-05 17:29:27 |
| R1.htm | 29291 | 2013-11-05 17:29:27 |
| R10.htm | 93170 | 2013-11-05 17:29:27 |
| R11.htm | 8358 | 2013-11-05 17:29:27 |
| R12.htm | 25578 | 2013-11-05 17:29:27 |
| R13.htm | 8659 | 2013-11-05 17:29:27 |
| R14.htm | 47570 | 2013-11-05 17:29:27 |
| R15.htm | 195374 | 2013-11-05 17:29:27 |
| R16.htm | 98644 | 2013-11-05 17:29:27 |
| R17.htm | 218379 | 2013-11-05 17:29:27 |
| R18.htm | 91210 | 2013-11-05 17:29:27 |
| R19.htm | 24442 | 2013-11-05 17:29:27 |
| R2.htm | 103683 | 2013-11-05 17:29:27 |
| R20.htm | 81399 | 2013-11-05 17:29:27 |
| R21.htm | 23019 | 2013-11-05 17:29:27 |
| R22.htm | 30385 | 2013-11-05 17:29:27 |
| R23.htm | 20867 | 2013-11-05 17:29:27 |
| R24.htm | 8771 | 2013-11-05 17:29:27 |
| R25.htm | 28663 | 2013-11-05 17:29:27 |
| R26.htm | 18858 | 2013-11-05 17:29:27 |
| R27.htm | 30871 | 2013-11-05 17:29:27 |
| R28.htm | 71501 | 2013-11-05 17:29:27 |
| R29.htm | 61218 | 2013-11-05 17:29:27 |
| R3.htm | 15089 | 2013-11-05 17:29:27 |
| R30.htm | 18366 | 2013-11-05 17:29:27 |
| R31.htm | 29093 | 2013-11-05 17:29:27 |
| R32.htm | 13856 | 2013-11-05 17:29:27 |
| R33.htm | 9189 | 2013-11-05 17:29:27 |
| R34.htm | 307130 | 2013-11-05 17:29:27 |
| R4.htm | 62997 | 2013-11-05 17:29:27 |
| R5.htm | 16317 | 2013-11-05 17:29:27 |
| R6.htm | 69396 | 2013-11-05 17:29:27 |
| R7.htm | 11262 | 2013-11-05 17:29:27 |
| R8.htm | 157918 | 2013-11-05 17:29:27 |
| R9.htm | 216315 | 2013-11-05 17:29:27 |
| report.css | 2740 | 2013-11-05 17:29:27 |
| Show.js | 1410 | 2013-11-05 17:29:27 |