Subject: File No. SR-NASDAQ-2006-040
From: Louis Ploth, Jr.
Affiliation: VP and CFO, Repros Therapeutics Inc.

December 12, 2006

NASDAQ has always been responsive to our company's needs and has provided us with top quality service. Although I would prefer to not have a listing fee increase, I do appreciate NASDAQ's offer to include important services as an expense offset. Obviously, anytime additional competition is introduced into the marketplace the consumer wins and the competition is unhappy.