Series and Classes/Contracts Information:
| Existing | |||
| Status | Name | Ticker Symbol | |
| CIK 0000906185 | |||
| Series S000010394 | Janus Henderson Balanced Portfolio | ||
| Class/Contract C000028716 | Service Shares | ||
| Class/Contract C000028717 | Institutional Shares | JABLX | |
| Status | Name | Ticker Symbol | |
| CIK 0000906185 | |||
| Series S000010395 | Janus Henderson Research Portfolio | ||
| Class/Contract C000028718 | Service Shares | ||
| Class/Contract C000028719 | Institutional Shares | JAGRX | |
| Status | Name | Ticker Symbol | |
| CIK 0000906185 | |||
| Series S000010396 | Janus Henderson Enterprise Portfolio | ||
| Class/Contract C000028720 | Service Shares | ||
| Class/Contract C000028721 | Institutional Shares | JAAGX | |
| Status | Name | Ticker Symbol | |
| CIK 0000906185 | |||
| Series S000010397 | Janus Henderson Mid Cap Value Portfolio | ||
| Class/Contract C000028722 | Service Shares | ||
| Class/Contract C000028723 | Institutional Shares | JAMVX | |
| Status | Name | Ticker Symbol | |
| CIK 0000906185 | |||
| Series S000010402 | Janus Henderson Global Research Portfolio | ||
| Class/Contract C000028728 | Service Shares | ||
| Class/Contract C000028730 | Institutional Shares | JAWGX | |
| Status | Name | Ticker Symbol | |
| CIK 0000906185 | |||
| Series S000010404 | Janus Henderson Flexible Bond Portfolio | ||
| Class/Contract C000028733 | Service Shares | ||
| Class/Contract C000028734 | Institutional Shares | JAFLX | |
| Status | Name | Ticker Symbol | |
| CIK 0000906185 | |||
| Series S000010406 | Janus Henderson Forty Portfolio | ||
| Class/Contract C000028736 | Service Shares | ||
| Class/Contract C000028737 | Institutional Shares | JACAX | |
| Status | Name | Ticker Symbol | |
| CIK 0000906185 | |||
| Series S000010408 | Janus Henderson Global Technology and Innovation Portfolio | ||
| Class/Contract C000028740 | Service Shares | ||
| Class/Contract C000028742 | Institutional Shares | JGLTX | |
| Status | Name | Ticker Symbol | |
| CIK 0000906185 | |||
| Series S000010410 | Janus Henderson Overseas Portfolio | ||
| Class/Contract C000028745 | Service Shares | ||
| Class/Contract C000028747 | Institutional Shares | JAIGX | |
| Status | Name | Ticker Symbol | |
| CIK 0000906185 | |||
| Series S000038239 | Janus Henderson Adaptive Risk Managed U.S. Equity Portfolio | ||
| Class/Contract C000117905 | Service Shares | ||
| Status | Name | Ticker Symbol | |
| CIK 0000906185 | |||
| Series S000074910 | Janus Henderson Global Sustainable Equity Portfolio | ||
| Class/Contract C000233309 | Institutional Shares | JHISX | |
| Class/Contract C000233310 | Service Shares | ||
IRS No.: 841235540 | State of Incorp.: DE | Fiscal Year End: 1231
Type: N-CSR/A | Act: 40 | File No.: 811-07736 | Film No.: 23830506
