Document Format Files
| Seq | Description | Document | Type | Size |
|---|---|---|---|---|
| 1 | AMENDMENT NO. 1 TO FORM S-1 | d445892ds1a.htm | S-1/A | 2317656 |
| 2 | EX-1.1 | d445892dex11.htm | EX-1.1 | 168012 |
| 3 | EX-3.1 | d445892dex31.htm | EX-3.1 | 129158 |
| 4 | EX-3.1.1 | d445892dex311.htm | EX-3.1.1 | 9018 |
| 5 | EX-3.2 | d445892dex32.htm | EX-3.2 | 25820 |
| 6 | EX-3.4 | d445892dex34.htm | EX-3.4 | 156644 |
| 7 | EX-4.2 | d445892dex42.htm | EX-4.2 | 4243 |
| 8 | EX-5.1 | d445892dex51.htm | EX-5.1 | 7195 |
| 9 | EX-10.1 | d445892dex101.htm | EX-10.1 | 71178 |
| 10 | EX-10.3 | d445892dex103.htm | EX-10.3 | 261715 |
| 11 | EX-10.4 | d445892dex104.htm | EX-10.4 | 109408 |
| 12 | EX-23.1 | d445892dex231.htm | EX-23.1 | 2119 |
| 13 | GRAPHIC | g445001dsp_98.jpg | GRAPHIC | 5169 |
| 14 | GRAPHIC | g445001dsp_99.jpg | GRAPHIC | 3277 |
| 15 | GRAPHIC | g445001page087.jpg | GRAPHIC | 229639 |
| 16 | GRAPHIC | g445001page088.jpg | GRAPHIC | 151085 |
| 17 | GRAPHIC | g445892g04o01.jpg | GRAPHIC | 98493 |
| 18 | GRAPHIC | g445892g08w61.jpg | GRAPHIC | 22094 |
| 19 | GRAPHIC | g445892g14u14.jpg | GRAPHIC | 49223 |
| 20 | GRAPHIC | g445892g15m65.jpg | GRAPHIC | 93233 |
| 21 | GRAPHIC | g445892g16u85.jpg | GRAPHIC | 70536 |
| 22 | GRAPHIC | g445892g21b91.jpg | GRAPHIC | 201279 |
| 23 | GRAPHIC | g445892g22t64.jpg | GRAPHIC | 236288 |
| 24 | GRAPHIC | g445892g22v77.jpg | GRAPHIC | 111161 |
| 25 | GRAPHIC | g445892g22x11.jpg | GRAPHIC | 70143 |
| 26 | GRAPHIC | g445892g25l12.jpg | GRAPHIC | 98282 |
| 27 | GRAPHIC | g445892g27f58.jpg | GRAPHIC | 114066 |
| 28 | GRAPHIC | g445892g29z89.jpg | GRAPHIC | 74702 |
| 29 | GRAPHIC | g445892g34p66.jpg | GRAPHIC | 68961 |
| 30 | GRAPHIC | g445892g35h73.jpg | GRAPHIC | 61429 |
| 31 | GRAPHIC | g445892g37k78.jpg | GRAPHIC | 53491 |
| 32 | GRAPHIC | g445892g40m34.jpg | GRAPHIC | 100834 |
| 33 | GRAPHIC | g445892g42j93.jpg | GRAPHIC | 72124 |
| 34 | GRAPHIC | g445892g47r89.jpg | GRAPHIC | 59893 |
| 35 | GRAPHIC | g445892g48n18.jpg | GRAPHIC | 57753 |
| 36 | GRAPHIC | g445892g51t17.jpg | GRAPHIC | 107104 |
| 37 | GRAPHIC | g445892g52v10.jpg | GRAPHIC | 61529 |
| 38 | GRAPHIC | g445892g55u07.jpg | GRAPHIC | 139357 |
| 39 | GRAPHIC | g445892g56u47.jpg | GRAPHIC | 192260 |
| 40 | GRAPHIC | g445892g59e32.jpg | GRAPHIC | 332387 |
| 41 | GRAPHIC | g445892g60f64.jpg | GRAPHIC | 90904 |
| 42 | GRAPHIC | g445892g64b12.jpg | GRAPHIC | 55892 |
| 43 | GRAPHIC | g445892g69k05.jpg | GRAPHIC | 220714 |
| 44 | GRAPHIC | g445892g69u03.jpg | GRAPHIC | 245161 |
| 45 | GRAPHIC | g445892g71n69.jpg | GRAPHIC | 73805 |
| 46 | GRAPHIC | g445892g72m83.jpg | GRAPHIC | 71054 |
| 47 | GRAPHIC | g445892g76i28.jpg | GRAPHIC | 65226 |
| 48 | GRAPHIC | g445892g79n86.jpg | GRAPHIC | 172707 |
| 49 | GRAPHIC | g445892g79t94.jpg | GRAPHIC | 170538 |
| 50 | GRAPHIC | g445892g85a15.jpg | GRAPHIC | 183235 |
| 51 | GRAPHIC | g445892g86j38.jpg | GRAPHIC | 119395 |
| 52 | GRAPHIC | g445892g87b50.jpg | GRAPHIC | 77473 |
| 53 | GRAPHIC | g445892g88j40.jpg | GRAPHIC | 149616 |
| 54 | GRAPHIC | g445892g96q17.jpg | GRAPHIC | 105069 |
| 55 | GRAPHIC | g445892g98t48.jpg | GRAPHIC | 66029 |
| 56 | GRAPHIC | g445892g98v06.jpg | GRAPHIC | 156454 |
| Complete submission text file | 0001193125-17-351618.txt | 10083332 |
IRS No.: 463872213 | State of Incorp.: DE | Fiscal Year End: 1231
Type: S-1/A | Act: 33 | File No.: 333-221522 | Film No.: 171221846
SIC: 2836 Biological Products, (No Diagnostic Substances)
