Document Format Files
| Seq | Description | Document | Type | Size |
|---|---|---|---|---|
| 1 | S-1 | a2226902zs-1.htm | S-1 | 2655403 |
| 2 | EX-3.1 | a2226902zex-3_1.htm | EX-3.1 | 178070 |
| 3 | EX-3.2 | a2226902zex-3_2.htm | EX-3.2 | 139274 |
| 4 | EX-3.3 | a2226902zex-3_3.htm | EX-3.3 | 67544 |
| 5 | EX-3.4 | a2226902zex-3_4.htm | EX-3.4 | 209276 |
| 6 | EX-4.1 | a2226902zex-4_1.htm | EX-4.1 | 11718 |
| 7 | EX-10.1 | a2226902zex-10_1.htm | EX-10.1 | 550453 |
| 8 | EX-10.2 | a2226902zex-10_2.htm | EX-10.2 | 107096 |
| 9 | EX-10.3 | a2226902zex-10_3.htm | EX-10.3 | 272529 |
| 10 | EX-10.4 | a2226902zex-10_4.htm | EX-10.4 | 553472 |
| 11 | EX-10.5 | a2226902zex-10_5.htm | EX-10.5 | 98640 |
| 12 | EX-10.6 | a2226902zex-10_6.htm | EX-10.6 | 75428 |
| 13 | EX-10.7 | a2226902zex-10_7.htm | EX-10.7 | 73898 |
| 14 | EX-10.8 | a2226902zex-10_8.htm | EX-10.8 | 76496 |
| 15 | EX-10.9 | a2226902zex-10_9.htm | EX-10.9 | 116724 |
| 16 | EX-10.10 | a2226902zex-10_10.htm | EX-10.10 | 98571 |
| 17 | EX-10.11 | a2226902zex-10_11.htm | EX-10.11 | 42538 |
| 18 | EX-10.12 | a2226902zex-10_12.htm | EX-10.12 | 39371 |
| 19 | EX-10.13 | a2226902zex-10_13.htm | EX-10.13 | 164822 |
| 20 | EX-10.14 | a2226902zex-10_14.htm | EX-10.14 | 91190 |
| 21 | EX-10.15 | a2226902zex-10_15.htm | EX-10.15 | 96555 |
| 22 | EX-10.16 | a2226902zex-10_16.htm | EX-10.16 | 109994 |
| 23 | EX-10.17 | a2226902zex-10_17.htm | EX-10.17 | 2198716 |
| 24 | EX-10.18 | a2226902zex-10_18.htm | EX-10.18 | 2248599 |
| 25 | EX-10.19 | a2226902zex-10_19.htm | EX-10.19 | 322981 |
| 26 | EX-10.20 | a2226902zex-10_20.htm | EX-10.20 | 399278 |
| 27 | EX-10.21 | a2226902zex-10_21.htm | EX-10.21 | 122181 |
| 28 | EX-10.22 | a2226902zex-10_22.htm | EX-10.22 | 1474704 |
| 29 | EX-10.23 | a2226902zex-10_23.htm | EX-10.23 | 603495 |
| 30 | EX-10.24 | a2226902zex-10_24.htm | EX-10.24 | 14567 |
| 31 | EX-10.25 | a2226902zex-10_25.htm | EX-10.25 | 53473 |
| 32 | EX-10.26 | a2226902zex-10_26.htm | EX-10.26 | 368901 |
| 33 | EX-10.27 | a2226902zex-10_27.htm | EX-10.27 | 97008 |
| 34 | EX-10.28 | a2226902zex-10_28.htm | EX-10.28 | 95889 |
| 35 | EX-21.1 | a2226902zex-21_1.htm | EX-21.1 | 3530 |
| 36 | EX-23.1 | a2226902zex-23_1.htm | EX-23.1 | 2726 |
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| 39 | G203902KM03I001.GIF | g203902km03i001.gif | GRAPHIC | 107548 |
| 40 | G203902KS01I001.GIF | g203902ks01i001.gif | GRAPHIC | 4944 |
| 41 | G203902KS03I001.GIF | g203902ks03i001.gif | GRAPHIC | 4944 |
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| 43 | G203902KT03I001.JPG | g203902kt03i001.jpg | GRAPHIC | 4285 |
| 44 | G203902LK01I001.GIF | g203902lk01i001.gif | GRAPHIC | 7390 |
| 45 | G203902LO01I001.JPG | g203902lo01i001.jpg | GRAPHIC | 3642 |
| 46 | G203902LQ01I001.GIF | g203902lq01i001.gif | GRAPHIC | 7390 |
| 47 | G203902LT19I001.GIF | g203902lt19i001.gif | GRAPHIC | 191034 |
| 48 | G203902LT21I001.GIF | g203902lt21i001.gif | GRAPHIC | 141642 |
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| 51 | G203902LT23I003.GIF | g203902lt23i003.gif | GRAPHIC | 170242 |
| 52 | G203902LT23I004.GIF | g203902lt23i004.gif | GRAPHIC | 159164 |
| 53 | G203902LT35I001.GIF | g203902lt35i001.gif | GRAPHIC | 30906 |
| 54 | G203902LT39I001.JPG | g203902lt39i001.jpg | GRAPHIC | 100963 |
| 55 | G203902LT43I001.JPG | g203902lt43i001.jpg | GRAPHIC | 37236 |
| 56 | G203902LT43I002.JPG | g203902lt43i002.jpg | GRAPHIC | 52088 |
| 57 | G203902LT43I003.JPG | g203902lt43i003.jpg | GRAPHIC | 91561 |
| 58 | G203902LT43I004.JPG | g203902lt43i004.jpg | GRAPHIC | 70428 |
| 59 | G203902LT43I005.JPG | g203902lt43i005.jpg | GRAPHIC | 46925 |
| 60 | G203902LT47I001.JPG | g203902lt47i001.jpg | GRAPHIC | 80983 |
| 61 | G203902LT47I002.JPG | g203902lt47i002.jpg | GRAPHIC | 47491 |
| 62 | G203902LT47I003.JPG | g203902lt47i003.jpg | GRAPHIC | 68252 |
| 63 | G203902LT49I001.GIF | g203902lt49i001.gif | GRAPHIC | 15892 |
| 64 | G203902LT53I001.GIF | g203902lt53i001.gif | GRAPHIC | 169635 |
| 65 | G203902LT57I001.GIF | g203902lt57i001.gif | GRAPHIC | 139688 |
| 66 | G203902LU19I001.GIF | g203902lu19i001.gif | GRAPHIC | 191132 |
| 67 | G203902LU21I001.GIF | g203902lu21i001.gif | GRAPHIC | 141513 |
| 68 | G203902LU23I001.GIF | g203902lu23i001.gif | GRAPHIC | 222403 |
| 69 | G203902LU23I002.GIF | g203902lu23i002.gif | GRAPHIC | 155132 |
| 70 | G203902LU23I003.GIF | g203902lu23i003.gif | GRAPHIC | 170242 |
| 71 | G203902LU23I004.GIF | g203902lu23i004.gif | GRAPHIC | 159164 |
| 72 | G203902LU35I001.GIF | g203902lu35i001.gif | GRAPHIC | 30918 |
| 73 | G203902LU39I001.JPG | g203902lu39i001.jpg | GRAPHIC | 100963 |
| 74 | G203902LU43I001.JPG | g203902lu43i001.jpg | GRAPHIC | 37236 |
| 75 | G203902LU43I002.JPG | g203902lu43i002.jpg | GRAPHIC | 52088 |
| 76 | G203902LU43I003.JPG | g203902lu43i003.jpg | GRAPHIC | 91561 |
| 77 | G203902LU43I004.JPG | g203902lu43i004.jpg | GRAPHIC | 70428 |
| 78 | G203902LU43I005.JPG | g203902lu43i005.jpg | GRAPHIC | 46925 |
| 79 | G203902LU47I001.JPG | g203902lu47i001.jpg | GRAPHIC | 80983 |
| 80 | G203902LU47I002.JPG | g203902lu47i002.jpg | GRAPHIC | 47491 |
| 81 | G203902LU47I003.JPG | g203902lu47i003.jpg | GRAPHIC | 68252 |
| 82 | G203902LU49I001.GIF | g203902lu49i001.gif | GRAPHIC | 15892 |
| 83 | G203902LU53I001.GIF | g203902lu53i001.gif | GRAPHIC | 169635 |
| 84 | G203902LU57I001.GIF | g203902lu57i001.gif | GRAPHIC | 139688 |
| 85 | G203902MMI001.JPG | g203902mmi001.jpg | GRAPHIC | 5884 |
| 86 | G203902MMI002.JPG | g203902mmi002.jpg | GRAPHIC | 9173 |
| 87 | G203902MA17I001.JPG | g203902ma17i001.jpg | GRAPHIC | 3178 |
| 88 | G203902MA17I002.JPG | g203902ma17i002.jpg | GRAPHIC | 2759 |
| 89 | G203902NE09I001.JPG | g203902ne09i001.jpg | GRAPHIC | 55932 |
| 90 | G203902NE09I002.JPG | g203902ne09i002.jpg | GRAPHIC | 31054 |
| 91 | G203902NE11I001.JPG | g203902ne11i001.jpg | GRAPHIC | 2237 |
| 92 | G203902BCI001.JPG | g203902bci001.jpg | GRAPHIC | 1252 |
| 93 | G203902BCI002.GIF | g203902bci002.gif | GRAPHIC | 11274 |
| 94 | G713517.JPG | g713517.jpg | GRAPHIC | 17441 |
| 95 | G216994.JPG | g216994.jpg | GRAPHIC | 58547 |
| 96 | G300806.JPG | g300806.jpg | GRAPHIC | 22407 |
| 97 | G908147.JPG | g908147.jpg | GRAPHIC | 12211 |
| 98 | G18677.JPG | g18677.jpg | GRAPHIC | 68707 |
| 99 | G460148.JPG | g460148.jpg | GRAPHIC | 90822 |
| 100 | G372168.JPG | g372168.jpg | GRAPHIC | 80805 |
| 101 | G187422.JPG | g187422.jpg | GRAPHIC | 37523 |
| 102 | G432661.JPG | g432661.jpg | GRAPHIC | 64305 |
| 103 | G343910.JPG | g343910.jpg | GRAPHIC | 25087 |
| 104 | G336033.JPG | g336033.jpg | GRAPHIC | 18839 |
| 105 | G435075.JPG | g435075.jpg | GRAPHIC | 21257 |
| 106 | G320004.JPG | g320004.jpg | GRAPHIC | 20491 |
| 107 | G116910.JPG | g116910.jpg | GRAPHIC | 21950 |
| 108 | G659298.JPG | g659298.jpg | GRAPHIC | 35037 |
| 109 | G455569.JPG | g455569.jpg | GRAPHIC | 48794 |
| 110 | G624605.JPG | g624605.jpg | GRAPHIC | 32244 |
| 111 | G451105.JPG | g451105.jpg | GRAPHIC | 19954 |
| 112 | G944837.JPG | g944837.jpg | GRAPHIC | 17151 |
| 113 | G75865.JPG | g75865.jpg | GRAPHIC | 39161 |
| 114 | G293710.JPG | g293710.jpg | GRAPHIC | 26033 |
| 115 | filename115.htm | CORRESP | 10956 | |
| Complete submission text file | 0001047469-16-009534.txt | 20931369 |
IRS No.: 464097528 | State of Incorp.: DE | Fiscal Year End: 1231
Type: S-1 | Act: 33 | File No.: 333-208856 | Film No.: 161319009
SIC: 2836 Biological Products, (No Diagnostic Substances)
