Income Taxes (Details 2) (USD $) In Thousands, unless otherwise specified	12 Months Ended
	Dec. 31, 2012 Year
Operating Loss Carryforwards [Line Items]
Tax loss carryforwards	$ 150,126
Tax credit carryforward	3,730
Tax credit carryfoward, Carryfoward period, Minimum (in years)	1
Period over which company has not been in a cumulative loss position	3
U.S. [Member]
Operating Loss Carryforwards [Line Items]
Tax loss carryforwards	69,709
Federal [Member]
Operating Loss Carryforwards [Line Items]
Tax loss carryforwards, Carryforward period, Minimum (in years)	17
Tax loss carryforwards, Carryforward period, Maximum (in years)	19
State [Member]
Operating Loss Carryforwards [Line Items]
Tax loss carryforwards, Carryforward period, Minimum (in years)	1
International [Member]
Operating Loss Carryforwards [Line Items]
Tax loss carryforwards	74,225
Tax loss carryforwards, Carryforward period, Minimum (in years)	3
Tax loss carryforwards, Carryforward period, Maximum (in years)	15
International with Unlimited Carryforward Periods [Member]
Operating Loss Carryforwards [Line Items]
Tax loss carryforwards	6,192
Synventive [Member]
Operating Loss Carryforwards [Line Items]
Tax loss carryforwards	$ 12,977