X0508 4 2025-02-19 0000097745 THERMO FISHER SCIENTIFIC INC. TMO 0001777440 Lowery Frederick M. 168 THIRD AVENUE WALTHAM MA 02451 1 Executive Vice President 0 Common Stock 2025-02-19 4 A 0 1638 0 A 11911.0064 D Common Stock 2025-02-19 4 A 0 5043 0 A 16954.0064 D Common Stock 1146.39 I by 401K Common Stock 5.036 I by Limited Liability Company Stock Option (Right to Buy) 530.86 2025-02-19 4 A 0 10037 0 A 2035-02-19 Common Stock 10037 10037 D Shares represent a performance-based restricted stock unit award granted on February 21, 2024. The Company's Compensation Committee determined on February 19, 2025, that the performance criteria related to this award were satisfied. One-third of the shares vest on February 28, 2025 and 2026. The remaining one-third will vest on February 28, 2027, and is subject to adjustment (positive or negative) for long-term performance which is based on the comparison of the Company's total shareholder return compound annual growth rate ("CAGR") to the total shareholder return CAGR of each of the companies in the peer group, as specified within the award agreement, over the measurement period starting on January 1, 2024, through to December 31, 2026. Between August 23, 2024 and February 19, 2025, the reporting person acquired 4.12 shares of TMO common stock under the TMO 401(k) plan. The reporting person disclaims beneficial ownership of the securities reported herein as indirectly beneficially owned, except to the extent of any pecuniary interest therein. The option vests in four equal annual installments beginning on February 28, 2026. Exhibit List: Exhibit 24 - Confirming Statement /s/ Melodie T. Morin, Attorney-in-Fact for Frederick M. Lowery 2025-02-21