X0306 4 2022-02-23 0000097745 THERMO FISHER SCIENTIFIC INC. TMO 0001518973 Lagarde Michel 168 THIRD AVENUE WALTHAM MA 02451 1 Executive Vice President & COO Common Stock 2022-02-23 4 A 0 6081 0 A 22960.205 D Common Stock 2022-02-23 4 F 0 899 528.58 D 22061.205 D Common Stock 2022-02-23 4 A 0 1806 0 A 23867.205 D Common Stock 2022-02-23 4 F 0 864 528.58 D 23003.205 D Stock Option (Right to Buy) 528.58 2022-02-23 4 A 0 13941 0 A 2030-02-23 Common Stock 13941 13941 D Shares represent a performance-based restricted stock unit award granted on February 23, 2021. The Company's Compensation Committee determined on February 23, 2022, that the performance criteria related to this award were satisfied. One-third of the shares vested on February 23, 2022, and one-third of the shares vest on February 23, 2023. The remaining one-third will vest on February 23, 2024, and is subject to adjustment (positive or negative) for long-term performance which is based on the comparison of the Company's total shareholder return compound annual growth rate ("CAGR") to the total shareholder return CAGR of each of the companies in the peer group, as specified within the award agreement, over the measurement period starting on January 1, 2021, through to December 31, 2023. The option vests in four equal annual installments beginning on February 28, 2023. /s/ Melodie T. Morin, Attorney-in-Fact for Michel Lagarde 2022-02-25