X0306 4 2015-06-01 0000097745 THERMO FISHER SCIENTIFIC INC. TMO 0001380163 Malus Alan J 81 WYMAN STREET WALTHAM MA 02451 1 Executive Vice President Common Stock 2015-06-01 4 M 0 40350 36.10 A 95207 D Common Stock 2015-06-01 4 S 0 3901 128.97 D 91306 D Common Stock 2015-06-01 4 S 0 36449 129.60 D 54857 D Common Stock 14256 I By Spouse Stock Option (Right to Buy) 36.10 2015-06-01 4 M 0 40350 0 D 2016-02-26 Common Stock 40350 0 D The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on March 10, 2015. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $128.53 to $129.27, inclusive. The reporting person undertakes to provide to Thermo Fisher Scientific Inc. ("TMO"), any security holder of TMO or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnotes (2) and (3) to this Form 4. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $129.31 to $129.94, inclusive. The option vested in three equal installments on February 26, 2010, 2011, and 2012. /s/ Barbara J. Lucas, Attorney-in-Fact for Alan J. Malus 2015-06-02