X0508 4 2026-02-25 0000097745 THERMO FISHER SCIENTIFIC INC. TMO 0001777440 Lowery Frederick M. 168 THIRD AVENUE WALTHAM MA 02451 1 Executive Vice President 0 Common Stock 2026-02-25 4 A 0 1638 0 A 15941.3724 D Common Stock 1186.684 I by 401K Common Stock 5.036 I by Limited Liability Company Shares represent a performance-based restricted stock unit award granted on February 19, 2025. On February 25, 2026, the Compensation Committee certified achievement of the applicable performance criteria. The award vests in three equal tranches on February 28, 2026, 2027 and 2028, in accordance with the terms of the award agreement. Shares represent an adjustment to the final tranche of a performance-based restricted stock unit award granted on February 22, 2023. On February 25, 2026, the Compensation Committee certified a 15% reduction based on the Company's relative TSR performance over the three-year measurement period, resulting in 64 fewer shares than previously reported. Between December 2, 2025 and February 26, 2026, the reporting person acquired 10.854 shares of TMO common stock under the TMO 401(k) plan. The reporting person disclaims beneficial ownership of the securities reported herein as indirectly beneficially owned, except to the extent of any pecuniary interest therein. /s/ Melodie T. Morin, Attorney-in-Fact for Frederick M. Lowery 2026-02-27