Business Segment Information - Schedule of Business Segment Information (Details) - USD ($) $ in Millions	3 Months Ended		6 Months Ended
	Jun. 28, 2025	Jun. 29, 2024	Jun. 28, 2025	Jun. 29, 2024	Dec. 31, 2024
Segment Reporting Information [Line Items]
Total revenues	$ 10,855	$ 10,541	$ 21,219	$ 20,886
Selling, general and administrative expenses	2,140	2,111	4,218	4,293
Research and development expenses	352	339	695	670
Segment income	1,834	1,820	3,551	3,483
Restructuring and other costs	(82)	(77)	(180)	(106)
Amortization of acquisition-related intangible assets			(859)	(1,065)
Interest income	297	295	501	574
Interest expense	(404)	(354)	(707)	(717)
Other income/(expense)	(19)	5	(16)	14
Consolidated income before income taxes	1,709	1,765	3,329	3,354
Segment assets	101,230	98,496	101,230	98,496	$ 97,321
Purchases of property, plant and equipment	294	301	656	648
Depreciation of property, plant and equipment	256	276	532	562
Life Sciences Solutions
Segment Reporting Information [Line Items]
Total revenues	2,115	1,996	4,069	3,926
Analytical Instruments
Segment Reporting Information [Line Items]
Total revenues	1,669	1,727	3,346	3,356
Specialty Diagnostics
Segment Reporting Information [Line Items]
Total revenues	1,118	1,100	2,248	2,200
Laboratory Products and Biopharma Services
Segment Reporting Information [Line Items]
Total revenues	5,953	5,719	11,556	11,404
Segment Reconciling Items
Segment Reporting Information [Line Items]
Total revenues	501	470	983	930
Cost of revenues adjustments	(10)	(1)	(21)	(17)
Selling, general and administrative expenses adjustments	(20)	64	(34)	45
Restructuring and other costs	(82)	(77)	(180)	(106)
Amortization of acquisition-related intangible assets	(429)	(513)	(859)	(1,065)
Segment assets	87,013	85,247	87,013	85,247
Purchases of property, plant and equipment	25	15	61	38
Depreciation of property, plant and equipment	0	0	0	0
Segment Reconciling Items | Life Sciences Solutions
Segment Reporting Information [Line Items]
Total revenues	385	359	771	714
Segment Reconciling Items | Analytical Instruments
Segment Reporting Information [Line Items]
Total revenues	58	55	99	113
Segment Reconciling Items | Specialty Diagnostics
Segment Reporting Information [Line Items]
Total revenues	16	17	34	27
Segment Reconciling Items | Laboratory Products and Biopharma Services
Segment Reporting Information [Line Items]
Total revenues	42	39	79	76
Operating Segments
Segment Reporting Information [Line Items]
Total revenues	11,356	11,011	22,202	21,817
Segment income	2,375	2,347	4,644	4,625
Operating Segments | Life Sciences Solutions
Segment Reporting Information [Line Items]
Total revenues	2,499	2,355	4,840	4,640
Cost of revenues	925	860	1,781	1,680
Selling, general and administrative expenses	467	428	936	859
Research and development expenses	136	130	273	262
Other segment items	53	73	97	133
Segment income	919	865	1,753	1,705
Restructuring and other costs	(11)		(54)
Segment assets	3,142	3,025	3,142	3,025
Purchases of property, plant and equipment	25	26	69	51
Depreciation of property, plant and equipment	56	57	114	112
Operating Segments | Analytical Instruments
Segment Reporting Information [Line Items]
Total revenues	1,728	1,782	3,446	3,469
Cost of revenues	902	852	1,738	1,651
Selling, general and administrative expenses	318	305	633	623
Research and development expenses	145	139	282	270
Other segment items	37	47	69	86
Segment income	325	439	724	838
Restructuring and other costs	(10)		(14)
Segment assets	3,070	2,723	3,070	2,723
Purchases of property, plant and equipment	13	18	57	46
Depreciation of property, plant and equipment	26	25	50	50
Operating Segments | Specialty Diagnostics
Segment Reporting Information [Line Items]
Total revenues	1,134	1,117	2,282	2,227
Cost of revenues	640	623	1,319	1,251
Selling, general and administrative expenses	183	188	354	375
Research and development expenses	47	44	92	84
Other segment items	(42)	(37)	(93)	(76)
Segment income	306	299	610	593
Restructuring and other costs	(3)		(5)
Segment assets	1,295	1,188	1,295	1,188
Purchases of property, plant and equipment	25	21	58	53
Depreciation of property, plant and equipment	23	22	44	44
Operating Segments | Laboratory Products and Biopharma Services
Segment Reporting Information [Line Items]
Total revenues	5,995	5,758	11,635	11,480
Cost of revenues	4,683	4,504	9,107	9,004
Selling, general and administrative expenses	599	596	1,191	1,181
Research and development expenses	14	17	27	34
Other segment items	(126)	(104)	(246)	(228)
Segment income	825	745	1,557	1,489
Restructuring and other costs	(56)		(100)
Segment assets	6,711	6,314	6,711	6,314
Purchases of property, plant and equipment	206	220	412	460
Depreciation of property, plant and equipment	152	173	324	356
Elimination of intersegment revenues
Segment Reporting Information [Line Items]
Total revenues	(501)	(470)	(983)	(930)
Elimination of intersegment revenues | Specialty Diagnostics
Segment Reporting Information [Line Items]
Total revenues	(65)	(62)	(137)	(125)
Elimination of intersegment revenues | Laboratory Products and Biopharma Services
Segment Reporting Information [Line Items]
Total revenues	$ (238)	$ (233)	$ (453)	$ (457)