Business Segment and Geographical Information - Schedule of Business Segment Information (Details) - USD ($) $ in Millions	3 Months Ended		9 Months Ended
	Sep. 28, 2024	Sep. 30, 2023	Sep. 28, 2024	Sep. 30, 2023
Segment Reporting Information [Line Items]
Consolidated revenues	$ 10,598	$ 10,574	$ 31,484	$ 31,971
Segment Income	1,838	1,864	5,321	5,005
Restructuring and other costs	(45)	(84)	(151)	(379)
Amortization of acquisition-related intangible assets			(1,514)	(1,775)
Interest income	277	246	851	570
Interest expense	(356)	(359)	(1,073)	(985)
Other income/(expense)	(16)	14	(2)	(32)
Consolidated income before taxes	1,742	1,765	5,096	4,558
Total Reportable Segments
Segment Reporting Information [Line Items]
Segment Income	2,362	2,560	6,987	7,260
Total Reportable Segments | Life Sciences Solutions
Segment Reporting Information [Line Items]
Consolidated revenues	2,387	2,433	7,027	7,508
Segment Income	845	872	2,551	2,525
Restructuring and other costs	(10)		(26)
Total Reportable Segments | Analytical Instruments
Segment Reporting Information [Line Items]
Consolidated revenues	1,808	1,754	5,277	5,226
Segment Income	451	468	1,289	1,321
Restructuring and other costs	8		(2)
Total Reportable Segments | Specialty Diagnostics
Segment Reporting Information [Line Items]
Consolidated revenues	1,129	1,083	3,355	3,300
Segment Income	293	283	886	860
Restructuring and other costs	(7)		(12)
Total Reportable Segments | Laboratory Products and Biopharma Services
Segment Reporting Information [Line Items]
Consolidated revenues	5,740	5,728	17,221	17,322
Segment Income	773	937	2,262	2,554
Restructuring and other costs	(36)		(107)
Eliminations
Segment Reporting Information [Line Items]
Consolidated revenues	(467)	(424)	(1,397)	(1,385)
Segment Reconciling Items
Segment Reporting Information [Line Items]
Cost of revenues adjustments	(9)	(14)	(25)	(73)
Selling, general and administrative expenses adjustments	(21)	(14)	24	(28)
Restructuring and other costs	(45)	(84)	(151)	(379)
Amortization of acquisition-related intangible assets	$ (450)	$ (584)	$ (1,514)	$ (1,775)