Business Segment and Geographical Information - Schedule of Business Segment Information (Details) - USD ($) $ in Millions	3 Months Ended		6 Months Ended
	Jun. 29, 2024	Jul. 01, 2023	Jun. 29, 2024	Jul. 01, 2023
Segment Reporting Information [Line Items]
Total revenues	$ 10,541	$ 10,687	$ 20,886	$ 21,397
Segment Income	1,820	1,578	3,483	3,141
Restructuring and other costs	(77)	(183)	(106)	(295)
Amortization of acquisition-related intangible assets			(1,065)	(1,191)
Interest income	295	178	574	324
Interest expense	(354)	(326)	(717)	(626)
Other income/(expense)	5	0	14	(46)
Income before income taxes	1,765	1,430	3,354	2,793
Total Reportable Segments
Segment Reporting Information [Line Items]
Segment Income	2,347	2,370	4,625	4,700
Total Reportable Segments | Life Sciences Solutions
Segment Reporting Information [Line Items]
Total revenues	2,355	2,463	4,640	5,075
Segment Income	865	817	1,705	1,653
Restructuring and other costs	(14)		(16)
Total Reportable Segments | Analytical Instruments
Segment Reporting Information [Line Items]
Total revenues	1,782	1,749	3,469	3,472
Segment Income	439	432	838	853
Restructuring and other costs	(3)		(10)
Total Reportable Segments | Specialty Diagnostics
Segment Reporting Information [Line Items]
Total revenues	1,117	1,109	2,227	2,217
Segment Income	299	297	593	577
Restructuring and other costs	0		(5)
Total Reportable Segments | Laboratory Products and Biopharma Services
Segment Reporting Information [Line Items]
Total revenues	5,758	5,831	11,480	11,594
Segment Income	745	824	1,489	1,617
Restructuring and other costs	(57)		(71)
Eliminations
Segment Reporting Information [Line Items]
Total revenues	(470)	(465)	(930)	(961)
Segment Reconciling Items
Segment Reporting Information [Line Items]
Cost of revenues adjustments	(1)	(18)	(17)	(59)
Selling, general and administrative expenses adjustments	64	(6)	45	(14)
Restructuring and other costs	(77)	(183)	(106)	(295)
Amortization of acquisition-related intangible assets	$ (513)	$ (585)	$ (1,065)	$ (1,191)