Business Segment and Geographical Information - Schedule of Business Segment Information (Details) - USD ($) $ in Millions	3 Months Ended		6 Months Ended
	Jul. 01, 2023	Jul. 02, 2022	Jul. 01, 2023	Jul. 02, 2022
Segment Reporting Information [Line Items]
Revenues	$ 10,687	$ 10,970	$ 21,397	$ 22,788
Segment Income	1,578	2,001	3,141	4,822
Restructuring and other costs	(183)	(24)	(295)	(26)
Amortization of acquisition-related intangible assets			(1,191)	(1,209)
Interest income	178	36	324	54
Interest expense	(326)	(148)	(626)	(284)
Other income/(expense)	0	28	(46)	(135)
Income before income taxes	1,430	1,917	2,793	4,457
Total Reportable Segments
Segment Reporting Information [Line Items]
Segment Income	2,370	2,605	4,700	6,055
Total Reportable Segments | Life Sciences Solutions
Segment Reporting Information [Line Items]
Revenues	2,463	3,292	5,075	7,523
Segment Income	817	1,327	1,653	3,503
Restructuring and other costs	(20)		(80)
Total Reportable Segments | Analytical Instruments
Segment Reporting Information [Line Items]
Revenues	1,749	1,607	3,472	3,125
Segment Income	432	344	853	645
Restructuring and other costs	(23)		(23)
Total Reportable Segments | Specialty Diagnostics
Segment Reporting Information [Line Items]
Revenues	1,109	1,101	2,217	2,583
Segment Income	297	243	577	596
Restructuring and other costs	(2)		(10)
Total Reportable Segments | Laboratory Products and Biopharma Services
Segment Reporting Information [Line Items]
Revenues	5,831	5,537	11,594	10,979
Segment Income	824	691	1,617	1,311
Restructuring and other costs	(133)		(176)
Eliminations
Segment Reporting Information [Line Items]
Revenues	(465)	(567)	(961)	(1,422)
Segment Reconciling Items
Segment Reporting Information [Line Items]
Cost of revenues adjustments	(18)	(8)	(59)	(19)
Selling, general and administrative expenses adjustments	(6)	28	(14)	21
Restructuring and other costs	(183)	(24)	(295)	(26)
Amortization of acquisition-related intangible assets	$ (585)	$ (600)	$ (1,191)	$ (1,209)