SEC Form 4
FORM 4 UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940
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 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
1. Name and Address of Reporting Person*
MEISTER PAUL M
(Last) (First) (Middle)
81 WYMAN STREET
P.O. BOX 9046
(Street)
WALTHAM MA 024549046
(City) (State) (Zip)
2. Issuer Name and Ticker or Trading Symbol
THERMO FISHER SCIENTIFIC INC. [ TMO ] 		5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
X Director 10% Owner
Officer (give title below) Other (specify below)
3. Date of Earliest Transaction (Month/Day/Year)
11/10/2006
4. If Amendment, Date of Original Filed (Month/Day/Year)
 6. Individual or Joint/Group Filing (Check Applicable Line)
X Form filed by One Reporting Person
Form filed by More than One Reporting Person
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V Amount (A) or (D) Price
Common Stock 11/16/2006 M(1) 99,279 A $4.75 575,400 D
Common Stock 11/16/2006 S(1) 225,400 D $43.79(2) 350,000 D
Common Stock 11/17/2006 M(1) 424,600 A $4.75 774,600 D
Common Stock 11/17/2006 S(1) 424,600 D $43.87(3) 350,000 D
Common Stock 11/20/2006 M(1) 100,000 A $4.75 450,000 D
Common Stock 11/20/2006 S(1) 100,000 D $43.71(4) 350,000 D
Common Stock 11/10/2006 F 154,425 D $45.03 829,787 I By Trusts
Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 6. Date Exercisable and Expiration Date (Month/Day/Year) 7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Stock Option (Right to Buy) $4.75 11/20/2006 M(1) 100,000 11/09/2006 01/21/2008 Common Stock 100,000 $0 240,725 D
Stock Option (Right to Buy) $4.75 11/16/2006 M(1) 99,279 11/09/2006 01/21/2008 Common Stock 99,279 $0 765,325 D
Stock Option (Right to Buy) $4.75 11/17/2006 M(1) 424,600 11/09/2006 01/21/2008 Common Stock 424,600 $0 340,725 D
Explanation of Responses:
1. The exercise and sale of the option shares were accomplished pursuant to a 10b5-1(c) sales plan adopted on November 13, 2006.
2. The sales price shown is the average sales price for directly held shares and all option shares sold on November 16, 2006, actual denominations are as follows:4,200 shares at $43.70; 5,500 shares at $43.71; 10,200 shares at $43.72; 29,900 shares at $43.73; 13,000 shares at $43.74; 77,700 shares at $43.75; 1,700 shares at $43.76; 5,000 shares at $43.77; 5,100 shares at $43.78; 1,050 shares at $43.82; 1,650 shares at $43.83; 15,000 shares at $43.84; 11,400 shares at $43.85; 400 shares at $43.86; 8,500 shares at $43.90; 3,500 shares at $43.91; 23,200 shares at $43.95; 8,400 shares at $43.98.
3. The sales price shown is the average sales price for all option shares sold on November 17, 2006, actual denominations are as follows:13,600 shares at $43.55; 1,000 shares at $43.56; 1,800 shares at $43.57; 1,100 shares at $43.58; 600 shares at $43.59; 27,500 shares at $43.60; 1,600 shares at $43.61; 300 shares at $43.63; 800 shares at $43.64; 27,100 shares at $43.65; 7,400 shares at $43.66; 2,500 shares at $43.67; 28,200 shares at $43.68; 18,700 shares at $43.69; 20,200 shares at $43.70; 2,100 shares at $43.71; 3,400 shares at $43.72; 5,700 shares at $43.73; 6,400 shares at $43.74; 5,000 shares at $43.75; 25,000 shares at $43.80; 100 shares at $43.85; 1,300 shares at $43.86; 500 shares at $43.87; 2,100 shares at $43.88; 5,600 shares at $43.89; 15,400 shares at $43.90; 67,300 shares at $44.00; 23,500 shares at $44.05; 12,500 shares at $44.06; 3,300 shares at $44.08; 24,500 shares at $44.09; 66,400 shares at $44.10; 2,100 shares at $44.15.
4. The sales price shown is the average sales price for all option shares sold on November 20, 2006, actual denominations are as follows: 6,600 shares at $43.50; 400 shares at $43.52; 100 shares at $43.58; 1,100 shares at $43.59; 6,900 shares at $43.60; 300 shares at $43.61; 1,600 shares at $43.62; 20,000 shares at $43.67; 10,000 shares at $43.70; 300 shares at $43.71; 2,700 shares at $43.72; 25,000 shares at $43.75; 25,000 shares at $43.80.
By: Barbara J. Lucas, Attorney-in-Fact for Paul M. Meister 11/20/2006
** Signature of Reporting Person Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.