X0508 4 2024-01-22 0 0000949858 ACHIEVE LIFE SCIENCES, INC. ACHV 0001713369 Stewart Richard Alistair 22722 29TH DR SE SUITE 100 BOTHELL WA 98021 1 1 0 0 Executive Chairman 0 Performance Restricted Stock Unit (PRSU) 2024-01-22 4 A 0 140000 0.00 A 2028-01-22 Common Stock 140000 140000 D Stock Option (right to buy) 4.55 2024-01-22 4 A 0 60000 0.00 A 2034-01-22 Common Stock 60000 60000 D Each PRSU represents a contingent right to receive one share of the issuer's common stock at settlement. Pursuant to the terms of the award agreement governing the PRSU, the total number of shares underlying the PRSU vest on the achievement of one of certain milestones being met. The PRSUs will lapse in full if achievement of at least one of the milestones is not met. The options vest one-third on the first anniversary of January 22, 2024 and thereafter in monthly installments over 24 months. Sandra Thomson as attorney-in-fact for Richard Stewart 2024-01-24