0000949858 1 2026-03-24 2026-03-24 0000949858 2026-03-24 2026-03-24 0000949858 2 2026-03-24 2026-03-24 pure shares iso4217:USD N/A 0000949858 EX-FILING FEES S-8 S-8 Achieve Life Sciences, Inc. false false Equity Common stock, par value $0.001 per share true 2661699 4.05 10779880.95 0.0001381 1488.71 Equity Common stock, par value $0.001 per share true 532339 3.44 1831246.16 0.0001381 252.9 12611127.11 1741.61 0 1741.61 (1) Represents additional shares of Common Stock to be registered and available for grant under the Registrant’s 2018 Equity Incentive Plan (the “EIP”) resulting from the annual automatic increase in shares available for issuance under the EIP pursuant to the provision of the EIP providing for an annual automatic increase in the number of shares reserved for issuance under the EIP. (2) Estimated pursuant to Rules 457(c) and 457(h) under the Securities Act, solely for the purposes of calculating the registration fee and based on the average of the high and low prices of Common Stock as reported on The Nasdaq Stock Market LLC (“Nasdaq”) on March 20, 2026, which date is within five business days prior to the filing of this Registration Statement. (1) Represents additional shares of Common Stock to be registered and available for grant under the Registrant’s 2017 Employee Stock Purchase Plan (the “ESPP”) resulting from the annual automatic increase in shares available for issuance under the ESPP pursuant to the provision of the ESPP providing for an annual automatic increase in the number of shares reserved for issuance under the ESPP. (2) Estimated pursuant to Rules 457(c) and 457(h) under the Securities Act, solely for the purposes of calculating the registration fee and based on the average of the high and low prices of Common Stock as reported on Nasdaq on March 20, 2026, which date is within five business days prior to the filing of this Registration Statement, multiplied by 85%, which is the percentage of the price per share applicable to purchases under the ESPP.