Collaboration and Other Agreements - Celera Corporation, Narrative (Details) (USD $)	1 Months Ended	3 Months Ended
	Apr. 30, 2006	Mar. 31, 2015	Mar. 31, 2014
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Milestone payment for HDAC Inhibitor	two-thirds
Milestone Payment For HDAC Inhibitor Percentage	66.66%
Milestone Payment For Factor VIIa	one-third
Milestone Payment For Factor VIIa Percentage	33.33%
Celera Corporation Agreement [Member]
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Maximum milestone payments	97,000,000
Potential future milestone payments to be paid to Celera after regulatory approval	90.00%
Collaborative agreement, termination terms, days written notice to terminate agreement	60 days
Collaborative agreement, termination terms, days of written notice that breaching party has to cure a breach in contract before termination	90 days
Celera Corporation Agreement [Member] | IMBRUVICA [Member]
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Royalty Expense		$ 11,800,000	$ 3,900,000