Condensed Consolidated Statements of Operations (USD $) In Thousands, except Per Share data, unless otherwise specified	3 Months Ended		6 Months Ended
	Jun. 30, 2014	Jun. 30, 2013	Jun. 30, 2014	Jun. 30, 2013
Revenue:
Product revenue, net	$ 109,495	$ 0	$ 165,674	$ 0
License and milestone revenue	0	50,000	60,000	50,000
Collaboration services revenue	3,525	4,684	6,723	7,530
Total revenue	113,020	54,684	232,397	57,530
Costs and expenses:
Cost of goods sold	9,305	0	15,415	0
Research and development	45,668	45,300	80,960	81,084
Less: Excess Amounts related to Research and development (see Note 3)	0	(17,377)	0	(17,377)
Research and development, net	45,668	27,923	80,960	63,707
Selling, general and administrative	45,002	17,736	79,717	37,762
Less: Excess Amounts related to Selling, general and administrative (see Note 3)	0	(3,006)	0	(3,006)
Selling, general and administrative, net	45,002	14,730	79,717	34,756
Costs of collaboration (see Note 3)	50,095	0	75,130	0
Amortization of intangible assets (see Note 7)	154	0	154	0
Total costs and expenses	150,224	42,653	251,376	98,463
Income (loss) from operations	(37,204)	12,031	(18,979)	(40,933)
Interest income	82	110	162	186
Other expense, net	(116)	(133)	(158)	(130)
Income (loss) before income taxes	(37,238)	12,008	(18,975)	(40,877)
Income tax benefit	181	343	193	1,317
Net income (loss)	$ (37,057)	$ 12,351	$ (18,782)	$ (39,560)
Net income (loss) per share:
Basic (in dollars per share)	$ (0.49)	$ 0.17	$ (0.25)	$ (0.55)
Diluted (in dollars per share)	$ (0.49)	$ 0.16	$ (0.25)	$ (0.55)
Weighted average shares used to compute net income (loss) per share:
Basic (in shares)	75,139	72,953	74,947	71,948
Diluted (in shares)	75,139	77,194	74,947	71,948