X0303 4 2011-06-06 0000946840 VIROPHARMA INC VPHM 0001421915 Wolf John Peter III 730 STOCKTON DRIVE EXTON PA 19341 1 VP, General Counsel Employee Stock Option (Right to Buy) 17.98 2011-06-06 4 A 0 40261 A 2012-06-06 2021-06-06 Common Stock 40261 40261 D The options vest in four equal annual installments beginning on the first anniversary date from time of grant This is an option grant for which there is no purchase price. /s/ J. Peter Wolf 2011-06-07