Consolidated Statements of Cash Flows (USD $) In Thousands, unless otherwise specified	12 Months Ended
	Dec. 31, 2011	Dec. 31, 2010	Dec. 31, 2009
Cash flows from operating activities:
Net loss	$ (9,015)	$ (13,136)	$ (7,180)
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation of property and equipment	465	407	359
Amortization of patent, trademark rights, and royalty interest	165	373	381
Finance costs amortization and for Standby Financing	0	0	241
Redeemable warrants valuation adjustment	(2,425)	(879)	(6,258)
Equity based compensation (stock option, warrant and service expense)	377	740	826
Other-than-temporary impairment of marketable securities	69	0	0
Gain on disposal of equipment	0	0	(83)
Change in assets and liabilities:
Inventories	(110)	77	0
Prepaid expenses and other current assets	(253)	54	93
Other assets	6	(7)	(5)
Accounts payable	424	362	1,884
Accrued expenses	201	123	445
Net cash used in operating activities	(10,096)	(11,886)	(9,297)
Cash flows from investing activities:
Purchases of property, equipment and construction in progress	(1,802)	(729)	(332)
Additions to patent and trademark rights	(234)	(337)	(242)
Deposits on capital lease	(4)	(9)	0
Maturities of short-term and long-term investments	20,896	7,448	0
Purchase of short-term and long-term investments	(10,201)	(49,889)	0
Net cash provided by (used in) investing activities	8,655	(43,516)	(574)
Cash flows from financing activities:
Proceeds from sale of common stock, net of issuance costs	0	293	55,570
Payments on capital lease	(71)	(43)	0
Proceeds from Margin Account Loan	1,695	0	0
Proceeds from exercise of stock warrants and options	0	0	6,254
Net cash provided by financing activities	1,624	250	61,824
Net (decrease) increase in cash and cash equivalents	183	(55,152)	51,953
Cash and cash equivalents at beginning of year	2,920	58,072	6,119
Cash and cash equivalents at end of year	3,103	2,920	58,072
Supplemental disclosures of cash flow information:
Issuance of common stock for accounts payable and accrued expenses	71	329	1,382
Equipment acquired by capital lease	62	200	0
Unrealized losses on investments	(585)	(974)	0
Redeemable warrants valuation adjustment	(2,425)	(879)	(6,258)
Supplemental disclosure of cash flow information:
Cash paid for interest expense	$ 41	$ 11	$ 0