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Note 4 - Summary of Significant Accounting Policies (Details Textual) - USD ($) $ / shares in Units, $ in Millions		3 Months Ended
	Jan. 24, 2024	Mar. 31, 2025	Mar. 31, 2024	Dec. 31, 2024	Nov. 01, 2017
Foreign Currency Transaction Gain, before Tax		$ 0.1	$ 0.2
Common Stock, Par or Stated Value Per Share (in dollars per share)		$ 0.001		$ 0.001
Number of Shares of Common Stock Potentially Issuable upon the Exercise of Stock Options and Warrants (in shares)		1.6	5,600
Exchange and Termination Agreement with Deerfield Management Company, L.P. [Member]
Termination Agreement, Payable	$ 0.2
Stock Issued During Period, Shares, New Issues (in shares)	676
Common Stock, Par or Stated Value Per Share (in dollars per share)	$ 0.001
Deerfield Loan [Member] \| Exchange and Termination Agreement [Member] \| Deerfield Management, L.P. [Member]
Liability for Contingent Milestone Payment, Noncurrent					$ 15.0