Note 14 - Stock-based Compensation (Tables)

3 Months Ended

Mar. 31, 2025

Notes Tables

Disclosure of Share-Based Compensation Arrangements by Share-Based Payment Award [Table Text Block]

(in whole numbers)
Stock Options	Shares			Weighted- Average Exercise Price		Weighted- Average Remaining Contractual Term (In Yrs)
Outstanding at January 1, 2025		290		$	77,533.16
Forfeited or expired		(3	)		58,374.86
Outstanding at March 31, 2025		287		$	77,742.72		7.7
Vested and exercisable at March 31, 2025		142		$	155,795.47		7.0
Vested and expected to vest at March 31, 2025		272		$	78,185.50		7.7

Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block]

	Three Months Ended March 31,
(in thousands)	2025		2024
Research and development	$	23	$	51
General and administrative		49		200
Total	$	72	$	251