X0306 4 2022-07-26 0000946486 WINDTREE THERAPEUTICS INC /DE/ WINT 0001716213 Hamill John P. 2600 KELLY ROAD SUITE 100 WARRINGTON PA 18976 1 SVP & CFO Common Stock 2022-07-26 4 P 0 3000 0.3666 A 72800 D The shares were purchased in multiple trades at prices ranging from $0.3639 to $0.37. The price reported above reflects the weighted average purchase price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. /s/ John P. Hamill 2022-07-26