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Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($)
$ in Thousands
3 Months Ended
Mar. 31, 2020
Mar. 31, 2019
Cash flows from operating activities:    
Net loss $ (6,534) $ (6,537)
Adjustments to reconcile net loss to net cash used in operating activities:    
Recognition of deferred revenue (40)
Depreciation 42 50
Amortization of debt discount 3 55
Stock-based compensation 1,689 1,530
Non-cash lease expense 177 192
Realized gain on investments (11)
Changes in:    
Prepaid expenses and other current assets (16) 5
Accounts payable (307) (2,003)
Collaboration and device development payable (108) (692)
Accrued expenses (238) (1,118)
Operating lease liabilities (190) (214)
Other liabilities 24
Net cash used in operating activities (5,482) (8,759)
Cash flows from investing activities:    
Purchase of property and equipment (74)
Sale of marketable securities 499
Net cash used in investing activities 425
Cash flows from financing activities:    
Repayment of loan payable (199) (447)
Payments for taxes related to net share settlements of restricted stock units (151)
Net cash provided by financing activities (199) (598)
Effect of exchange rates on cash and cash equivalents (98) (202)
Net increase/(decrease) in cash and cash equivalents (5,779) (9,134)
Cash, cash equivalents and restricted cash - beginning of year 22,732 11,358
Cash, cash equivalents and restricted cash - end of year $ 16,953 $ 2,224