Note 8 - Property and Equipment - Property and Equipment (Details) - USD ($) $ in Thousands	Dec. 31, 2019	Dec. 31, 2018
Property and equipment, gross	$ 7,172	$ 7,218
Accumulated depreciation and amortization	(6,374)	(6,416)
Property and equipment, net	798	802
Manufacturing, Laboratory, and Office Equipment [Member]
Property and equipment, gross	4,313	4,359
Furniture and Fixtures [Member]
Property and equipment, gross	390	390
Leasehold Improvements [Member]
Property and equipment, gross	$ 2,469	$ 2,469

Amount of accumulated depreciation, depletion and amortization for physical assets used in the normal conduct of business to produce goods and services.

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Amount before accumulated depreciation, depletion and amortization of physical assets used in the normal conduct of business and not intended for resale. Examples include, but are not limited to, land, buildings, machinery and equipment, office equipment, and furniture and fixtures.

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Amount after accumulated depreciation, depletion and amortization of physical assets used in the normal conduct of business to produce goods and services and not intended for resale. Examples include, but are not limited to, land, buildings, machinery and equipment, office equipment, and furniture and fixtures.

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