Note 20 - Income Taxes (Tables)

12 Months Ended

Dec. 31, 2019

Notes Tables

Schedule of Effective Income Tax Rate Reconciliation [Table Text Block]

	December 31,
(in thousands)	2019			2018
Income tax benefit, statutory rates	$	(5,770	)	$	(4,312	)
State taxes on income, net of federal benefit		(1,182	)		(535	)
Impact of tax reform		-			5
Research and development tax credit		(934	)		(351	)
Foreign rate differential		22			24
Employee related and other		1,983			2,875
Interest related		79			186
Income tax expense / (benefit), statutory rates		(5,802	)		(2,108	)
Valuation allowance		5,802			2,108
Income tax benefit, net	$	-		$	-

Schedule of Deferred Tax Assets and Liabilities [Table Text Block]

	December 31,
(in thousands)	2019			2018
Long-term deferred assets:
Net operating loss carryforwards (federal and state)	$	180,979		$	176,759
Research and development tax credit		17,599			16,718
Compensation expense on stock		2,142			1,121
Charitable contribution carryforward		-			-
Other accrued		934			1,016
Deferred revenue		-			57
Depreciation		128			309
Total long-term deferred tax assets		201,782			195,980
Long-term deferred liabilities:
IPRD		(15,419	)		(15,476	)
Total long-term deferred tax liabilities		(15,419	)		(15,476	)
Valuation allowance		(201,782	)		(195,980	)
Deferred tax liabilities, net	$	(15,419	)	$	(15,476	)