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Note 22 - Selected Quarterly Financial Data (Unaudited) (Tables)
 12 Months Ended
Dec. 31, 2019
Notes Tables  
Quarterly Financial Information [Table Text Block]
2019 Quarters Ended:
  
 
 
 
  
 
 
 
  
 
 
 
  
 
 
 
  
 
 
 
(in thousands, except per share data)
  
Mar. 31
    
June 30
    
Sept. 30
    
Dec. 31
    
Total Year
  
Revenues:
                                        
Grant revenue
   $
-
     $
-
     $
-
     $
-
     $
-
  
License revenue with affiliate
    
40
      
158
      
-
      
-
      
198
  
Total revenues
    
40
      
158
      
-
      
-
      
198
  
Expenses:
                                        
Research and development
    
3,342
      
3,413
      
3,792
      
2,140
      
12,687
  
Selling, general and administrative
    
3,355
      
3,240
      
3,395
      
2,414
      
12,404
  
Total expenses
    
6,697
      
6,653
      
7,187
      
4,554
      
25,091
  
Operating loss
    
(6,657
 )    
(6,495
 )    
(7,187
 )    
(4,554
 )    
(24,893
 )
Other income / (expense), net
    
120
      
58
      
61
      
(2,821
 )    
(2,582
 )
Net (loss) / income
   $
(6,537
 )   $
(6,437
 )   $
(7,126
 )   $
(7,375
 )   $
(27,475
 )
Net (loss) / income per common share - basic and diluted
   $
(0.20
 )   $
(0.20
 )   $
(0.22
 )   $
(0.21
 )   $
(0.84
 )
Weighted average number of common shares outstanding - basic and diluted
    
32,142
      
32,189
      
32,189
      
34,597
      
32,784
  
2018 Quarters Ended:
  
 
 
 
  
 
 
 
  
 
 
 
  
 
 
 
  
 
 
 
(in thousands, except per share data)
  
Mar. 31
    
June 30
    
Sept. 30
    
Dec. 31
    
Total Year
  
Revenues:
                                        
Grant revenue
   $
-
     $
695
     $
70
     $
-
     $
765
  
License revenue with affiliate
    
204
      
356
      
159
      
304
      
1,023
  
Total revenues
    
204
      
1,051
      
229
      
304
      
1,788
  
Expenses:
                                        
Research and development
    
3,118
      
2,879
      
2,197
      
2,368
      
10,562
  
Selling, general and administrative
    
1,926
      
1,208
      
1,500
      
2,787
      
7,421
  
Total expenses
    
5,044
      
4,087
      
3,697
      
5,155
      
17,983
  
Operating loss
    
(4,840
 )    
(3,036
 )    
(3,468
 )    
(4,851
 )    
(16,195
 )
Other income / (expense), net
    
328
      
(16
 )    
(459
 )    
(4,191
 )    
(4,338
 )
Net (loss) / income
   $
(4,512
 )   $
(3,052
 )   $
(3,927
 )   $
(9,042
 )   $
(20,533
 )
AEROSURF warrant dividend
    
-
      
-
      
-
      
(12,505
 )    
(12,505
 )
Deemed dividend on preferred stock
    
-
      
-
      
-
      
(1,718
 )    
(1,718
 )
Net (loss) / income attributable to common shareholders
   $
(4,512
 )   $
(3,052
 )   $
(3,927
 )   $
(23,265
 )   $
(34,756
 )
Net (loss) / income per common share - basic and diluted
   $
(1.40
 )   $
(0.81
 )   $
(1.04
 )   $
(3.24
 )   $
(7.74
 )
Weighted average number of common shares outstanding - basic and diluted
    
3,227
      
3,751
      
3,769
      
7,191
      
4,493