X0306 4 2016-08-04 0000946486 WINDTREE THERAPEUTICS INC /DE/ WINT 0001135563 ROSENTHALE MARVIN E 2600 KELLY ROAD SUITE 100 WARRINGTON PA 18976 1 Common Stock 2016-08-04 4 A 0 4348 0 A 6211 D Common Stock 595 I By Spouse Common Stock 1071 I By Trust Non-Qualified Stock Option (Right to Buy) 1.84 2016-08-04 4 A 0 15000 0 A 2017-08-04 2026-08-04 Common Stock 15000 15000 D Restricted stock units (RSUs), which represent a contingent right to receive the equivalent number of shares of common stock. The RSUs shall fully vest upon the first anniversary of the grant date or as provided under the Award Agreement and 2011 Plan. Adjusted to reflect 1-for-14 reverse stock split effective January 22, 2016. Dr. Rosenthale disclaims beneficial ownership of shares held by, or for the benefit of, his spouse. Shares held by the Marvin and Patricia Rosenthale Family Revocable Trust; Marvin and Patricia Rosenthale, Trustees. Stock option shall fully vest upon the first anniversary of the grant date or as provided under the Award Agreement and 2011 Plan. /s/ Mary B. Templeton, Esq., as Attorney-in-Fact 2016-08-08