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Stock Options and Stock-based Employee Compensation (Tables)
12 Months Ended
Dec. 31, 2014
Stock Options and Stock-based Employee Compensation [Abstract]  
Stock options and restricted stock units (RSUs) outstanding and available for future issuance
Stock options and restricted stock units (RSUs) outstanding and available for future issuance are as follows:

 
December 31,
 
  
2014
  
2013
 
     
Stock Options and RSUs Outstanding
    
2011 Plan
  
6,113
   
4,919
 
2007 Plan
  
257
   
258
 
1998 Plan
  
182
   
251
 
Total Outstanding
  
6,552
   
5,428
 
         
Available for Future Grants under 2011 Plan
  
6,667
   
2,894
 
Summary of stock option activity
A summary of activity under our long-term incentive plans is presented below:

(in thousands, except for weighted-average data)
     
Stock Options
 
Shares
  
Weighted-
Average
Exercise
Price
 
Weighted-
Average
Remaining
Contractual
Term (In Yrs)
 
      
Outstanding at January 1, 2014
  
5,428
  
$
6.51
  
          
Granted
  
1,786
   
2.39
  
Exercised
  
(17
)
  
1.83
  
Forfeited or expired
  
(663
)
  
15.57
  
Outstanding at December 31, 2014
  
6,534
  
$
4.50
   
7.3
 
             
Exercisable at December 31, 2014
  
3,599
  
$
6.23
   
6.3
 

(in thousands, except for weighted-average data)
    
Restricted Stock Units
 
Shares
  
Weighted-
Average
Grant
Date Fair
Value
 
     
Unvested at January 1, 2014
  
19
  
$
1.69
 
Awarded
  
36
  
$
1.71
 
Vested
  
(36
)
 
$
1.70
 
Unvested at December 31, 2014
  
19
  
$
1.71
 
Employee stock-based compensation
Stock-based compensation expense was classified as follows:

  
December 31,
 
(in thousands)
 
2014
  
2013
  
2012
 
       
Research and development
 
$
1,014
  
$
784
  
$
487
 
Selling, general and administrative
  
1,927
   
1,426
   
1,924
 
Total
 
$
2,941
  
$
2,210
  
$
2,411
 
Weighted-average assumptions in estimating fair value of options
The risk-free interest rates are based upon the U.S. Treasury yield curve in effect at the time of the grant.

  
December 31,
 
  
2014
  
2013
  
2012
 
       
Weighted average expected volatility
  
100%
 
  
109%
 
  
111%
 
Weighted average expected term
 
5.4 years
  
4.7 years
  
4.6 years
 
Weighted average risk-free interest rate
  
1.65%
 
  
0.73%
 
  
0.74%
 
Expected dividends