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Selected Quarterly Financial Data (Unaudited)
12 Months Ended
Dec. 31, 2014
Selected Quarterly Financial Data (Unaudited) [Abstract]  
Selected Quarterly Financial Data (Unaudited)
Note 16 –Selected Quarterly Financial Data (Unaudited)

The following tables contain unaudited statement of operations information for each quarter of 2014 and 2013.  The operating results for any quarter are not necessarily indicative of results for any future period.
 
2014 Quarters Ended:
        
(in thousands, except per share data)
 
Mar. 31
  
June 30
  
Sept. 30
  
Dec. 31
  
Total Year
 
Revenues:
          
Product sales
 
$
28
  
$
42
  
$
106
  
$
136
  
$
312
 
Grant revenues
  
3
   
1,051
   
421
   
1,048
   
2,523
 
Total revenues
  
31
   
1,093
   
527
   
1,184
   
2,835
 
Expenses:
                    
Cost of sales
  
781
   
731
   
257
   
902
   
2,671
 
Research and development
  
5,590
   
6,858
   
6,471
   
7,771
   
26,690
 
Selling, General and administrative
  
4,423
   
4,446
   
4,126
   
3,737
   
16,732
 
Total expenses
  
10,794
   
12,035
   
10,854
   
12,410
   
46,093
 
Operating loss
  
(10,763
)
  
(10,942
)
  
(10,327
)
  
(11,226
)
  
(43,258
)
Change in fair value of common stock warrant liability
  
378
   
1,448
   
173
   
1,792
   
3,791
 
Other expense, net
  
(1,091
)
  
(1,129
)
  
(1,170
)
  
(1,201
)
  
(4,591
)
Net loss
 
$
(11,476
)
 
$
(10,623
)
 
$
(11,324
)
 
$
(10,635
)
 
$
(44,058
)
Net loss per common share - basic
 
$
(0.14
)
 
$
(0.12
)
 
$
(0.13
)
 
$
(0.12
)
 
$
(0.52
)
Net loss per common share - diluted
  
(0.14
)
  
(0.14
)
  
(0.13
)
  
(0.15
)
  
(0.56
)
Weighted average number of common shares outstanding - basic
  
84,728
   
85,061
   
85,209
   
85,358
   
85,095
 
Weighted average number of common shares outstanding - diluted
  
84,728
   
85,882
   
85,209
   
85,560
   
86,025
 
 
2013 Quarters Ended:
         
(in thousands, except per share data)
 
Mar. 31
  
June 30
  
Sept. 30
  
Dec. 31
  
Total Year
 
Grant revenues
 
$
72
  
$
182
  
$
60
  
$
74
  
$
388
 
Expenses:
                    
Cost of sales
  
   
   
   
517
   
517
 
Research and development
  
8,472
   
6,863
   
6,574
   
5,752
   
27,661
 
Selling, General and administrative
  
4,220
   
4,129
   
4,299
   
4,070
   
16,718
 
Total expenses
  
12,692
   
10,992
   
10,873
   
10,339
   
44,896
 
Operating loss
  
(12,620
)
  
(10,810
)
  
(10,813
)
  
(10,265
)
  
(44,508
)
Change in fair value of common stock warrant liability
  
162
   
2,525
   
(1,059
)
  
(867
)
  
761
 
Other expense, net
  
(177
)
  
(342
)
  
(352
)
  
(597
)
  
(1,468
)
Net loss
 
$
(12,635
)
 
$
(8,627
)
 
$
(12,224
)
 
$
(11,729
)
 
$
(45,215
)
Net loss per common share - basic
 
$
(0.29
)
 
$
(0.18
)
 
$
(0.22
)
 
$
(0.16
)
 
$
(0.82
)
Net loss per common share - diluted
  
(0.29
)
  
(0.22
)
  
(0.22
)
  
(0.16
)
  
(0.82
)
Weighted average number of common shares outstanding - basic
  
43,657
   
49,135
   
54,792
   
73,129
   
55,258
 
Weighted average number of common shares outstanding - diluted
  
43,657
   
49,866
   
54,792
   
73,129
   
55,258