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Stock Options and Stock-based Employee Compensation (Details) (USD $)
In Thousands, unless otherwise specified
3 Months Ended
Mar. 31, 2013
Mar. 31, 2012
Stock Options and Stock-based Employee Compensation [Abstract]    
Weighted-average vesting period of stock options 3 years  
Weighted-average assumptions used in estimating fair value of stock options [Abstract]    
Weighted average expected volatility (in hundredths) 110.00% 113.00%
Weighted average expected term 4 years 9 months 18 days 4 years 9 months 18 days
Weighted average risk-free interest rate (in hundredths) 0.74% 0.79%
Expected dividends (in hundredths) 0.00% 0.00%
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]    
Employee stock-based compensation $ 356 $ 398
Research and Development [Member]
   
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]    
Employee stock-based compensation 141 120
Selling, General & Administrative [Member]
   
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]    
Employee stock-based compensation $ 215 $ 278