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Corporate Partnership, Licensing and Research Funding Agreements (Details) (USD $)
12 Months Ended
Dec. 31, 2012
Laboratories del Dr. Esteve, S.A. [Abstract]  
Percent of cash upfront and milestone fees payable to Esteve 10.00%
Maximum aggregate cash upfront and milestone fees payable to Esteve $ 20,000,000
Licensing and Research Funding Agreements [Abstract]  
Potential license fee payable 2,500,000
License fees paid 950,000
Payment of license costs subject to FDA approval $ 500,000