X0303 4 2010-01-03 0 0000946486 DISCOVERY LABORATORIES INC /DE/ DSCO 0001366002 Miller Thomas F 2600 KELLY ROAD SUITE 100 WARRINGTON PA 18976-3646 0 1 0 0 SVP, Commercial & Corp Dev Common Stock 2010-01-03 4 F 0 1105 0.63 D 6895 D Common Stock 2010-03-31 4 A 0 3966 0.52 A 25995 I by Trust Common Stock 2010-06-30 4 A 0 10857 0.19 A 36852 I by Trust Shares withheld in settlment of tax libilities incurred upon the vesting of a restricted stock award on Janaury 3, 2010 Transaction reported on Table 1 represents issuer's matching stock contribution pursuant to a 401(k) program Thomas F. Miller 2010-07-29