Represents maximum regulatory milestone payments under collaborative agreement.

No definition available.

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Namespace Prefix:	opk_
Data Type:	xbrli:monetaryItemType
Balance Type:	debit
Period Type:	instant

- Definition

Represents upfront payments under collaborative agreement.

+ References

No definition available.

+ Details

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Namespace Prefix:	opk_
Data Type:	xbrli:monetaryItemType
Balance Type:	debit
Period Type:	instant

- Definition

Amount of monthly payments in year five for operating lease.

+ References

No definition available.

+ Details

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Namespace Prefix:	opk_
Data Type:	xbrli:monetaryItemType
Balance Type:	credit
Period Type:	instant

- Definition

Amount of monthly payments in first year for operating lease.

+ References

No definition available.

+ Details

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Namespace Prefix:	opk_
Data Type:	xbrli:monetaryItemType
Balance Type:	credit
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- Definition

Area of a real estate property.

+ References

No definition available.

+ Details

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Balance Type:	na
Period Type:	instant

- Definition

Face (par) amount of debt instrument at time of issuance.

+ References

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-Topic 835
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+ Details

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Namespace Prefix:	us-gaap_
Data Type:	xbrli:monetaryItemType
Balance Type:	credit
Period Type:	instant

- Definition

Amount of principal of debt issued.

+ References

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Balance Type:	credit
Period Type:	duration

- Definition

The percentage of ownership of common stock or equity participation in the investee accounted for under the equity method of accounting.

+ References

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Data Type:	dtr-types:percentItemType
Balance Type:	na
Period Type:	instant

- Definition

Amount of interest payable on debt, including, but not limited to, trade payables.

+ References

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-Topic 942
-SubTopic 210
-Name Accounting Standards Codification
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-Publisher FASB
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- Definition

Amount of transactions with related party during the financial reporting period.

+ References

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-Topic 850
-SubTopic 10
-Name Accounting Standards Codification
-Section 50
-Paragraph 1
-Subparagraph (c)
-Publisher FASB
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Period Type:	duration

Note 11 - Related Party Transactions (Details Textual)		3 Months Ended
Note 11 - Related Party Transactions (Details Textual)	Jan. 09, 2024 USD ($)	Mar. 31, 2025 USD ($)	Mar. 31, 2024 USD ($)	Dec. 31, 2024	Aug. 01, 2024 USD ($) a	Jul. 31, 2024 a	May 04, 2023 USD ($)
Beckman Coulter [Member]
Related Party Transaction, Amounts of Transaction		$ 600,000
Integrated DNA Technologies Inc. [Member]
Related Party Transaction, Amounts of Transaction		1,000,000
Leica Microsystems Inc. [Member]
Related Party Transaction, Amounts of Transaction		$ 100,000
Ruen-Hui Biopharmaceuticals, Inc. [Member]
Equity Method Investment, Ownership Percentage							10.00%
Ruen-Hui Biopharmaceuticals, Inc. [Member] \| License Agreement [Member]
Collaborative Arrangement, Upfront Payments							$ 150,000
Collaborative Arrangement, Maximum Regulatory Milestone Payments							$ 1,000,000
Pharmsynthez [Member]
Equity Method Investment, Ownership Percentage		6.00%
Xenetic [Member]
Equity Method Investment, Ownership Percentage		3.00%
Zebra [Member]
Equity Method Investment, Ownership Percentage		29.00%
ChromaDex Corporation [Member]
Equity Method Investment, Ownership Percentage		0.05%
COCP [Member]
Equity Method Investment, Ownership Percentage		2.00%
NIMS [Member]
Equity Method Investment, Ownership Percentage		1.00%
Eloxx [Member]
Equity Method Investment, Ownership Percentage		1.00%
LeaderMed [Member]
Equity Method Investment, Ownership Percentage		47.00%
GeneDx [Member]
Equity Method Investment, Ownership Percentage				2.20%
The 2029 Convertible Notes 1 [Member]
Debt Instrument, Face Amount	$ 230,000,000
The 2029 Convertible Notes 1 [Member] \| Convertible Debt [Member]
Debt Instrument, Issued, Principal	71,100,000
The 2023 Convertible Notes [Member]
Interest Payable	16,100,000
The 2023 Convertible Notes [Member] \| Convertible Debt [Member]
Debt Instrument, Face Amount	$ 55,000,000
Frost Real Estate Holdings, LLC [Member]
Area of Real Estate Property (Acre) \| a					26,328	29,500
Operating Leases, Monthly Payments, Year One					$ 91,000
Operating Leases, Monthly Payments, Year Five					$ 103,000
Executive Officer [Member] \| Reimbursement of Travel Expenses [Member]
Related Party Transaction, Amounts of Transaction		$ 0	$ 0