Note 5 - Composition of Certain Financial Statement Captions - Schedule of Goodwill (Details) $ in Thousands	9 Months Ended
Sep. 30, 2024 USD ($)
Goodwill, gross	$ 636,283
Goodwill, impairment	(38,023)
Goodwill, acquired (disposed of)	(63,318)
Goodwill, foreign exchange effect	926
Goodwill	535,868
Pharmaceutical [Member] \| CURNA [Member]
Goodwill, gross	4,827
Goodwill, impairment	(4,827)
Goodwill, acquired (disposed of)	0
Goodwill, foreign exchange effect	0
Goodwill	0
Pharmaceutical [Member] \| Rayaldee [Member]
Goodwill, gross	84,273
Goodwill, impairment	0
Goodwill, acquired (disposed of)	0
Goodwill, foreign exchange effect	925
Goodwill	85,198
Pharmaceutical [Member] \| FineTech [Member]
Goodwill, gross	11,698
Goodwill, impairment	(11,698)
Goodwill, acquired (disposed of)	0
Goodwill, foreign exchange effect	0
Goodwill	0
Pharmaceutical [Member] \| ModeX Therapeutics, Inc [Member]
Goodwill, gross	80,260
Goodwill, impairment	0
Goodwill, acquired (disposed of)	0
Goodwill, foreign exchange effect	0
Goodwill	80,260
Pharmaceutical [Member] \| OPKO Biologics [Member]
Goodwill, gross	139,784
Goodwill, impairment	0
Goodwill, acquired (disposed of)	0
Goodwill, foreign exchange effect	(0)
Goodwill	139,784
Pharmaceutical [Member] \| OPKO Chile [Member]
Goodwill, gross	3,642
Goodwill, impairment	0
Goodwill, acquired (disposed of)	0
Goodwill, foreign exchange effect	(81)
Goodwill	3,561
Pharmaceutical [Member] \| OPKO Health Europe [Member]
Goodwill, gross	7,276
Goodwill, impairment	0
Goodwill, acquired (disposed of)	0
Goodwill, foreign exchange effect	82
Goodwill	7,358
Pharmaceutical [Member] \| OPKO Mexico [Member]
Goodwill, gross	100
Goodwill, impairment	(100)
Goodwill, acquired (disposed of)	0
Goodwill, foreign exchange effect	0
Goodwill	0
Pharmaceutical [Member] \| Transition Therapeutics [Member]
Goodwill, gross	3,421
Goodwill, impairment	(3,421)
Goodwill, acquired (disposed of)	0
Goodwill, foreign exchange effect	0
Goodwill	0
Diagnostics [Member] \| BioReference [Member]
Goodwill, gross	283,025
Goodwill, impairment	0
Goodwill, acquired (disposed of)	(63,318)
Goodwill, foreign exchange effect	0
Goodwill	219,707
Diagnostics [Member] \| OPKO Diagnostics [Member]
Goodwill, gross	17,977
Goodwill, impairment	(17,977)
Goodwill, acquired (disposed of)	0
Goodwill, foreign exchange effect	0
Goodwill	$ 0

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Amount, after accumulated impairment loss, of asset representing future economic benefit arising from other asset acquired in business combination or from joint venture formation or both, that is not individually identified and separately recognized.

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