Amount of cash used in the repurchase of notes.

No definition available.

Name:	opk_CashUsedOrRepurchaseOfNotes
Namespace Prefix:	opk_
Data Type:	xbrli:monetaryItemType
Balance Type:	credit
Period Type:	instant

- Definition

The aggregated principle amount that was purchased on the closing date of the convertible note.

+ References

No definition available.

+ Details

Name:	opk_DebtInstrumentAggregatePrincipleAmountPurchasedOnClosingDate
Namespace Prefix:	opk_
Data Type:	xbrli:monetaryItemType
Balance Type:	credit
Period Type:	duration

- Definition

The increase (decrease) in the maximum number of shares issuable of convertible debt.

+ References

No definition available.

+ Details

Name:	opk_DebtInstrumentConvertibleDebtIncreaseDecreaseInMaximumSharesIssuable
Namespace Prefix:	opk_
Data Type:	xbrli:sharesItemType
Balance Type:	na
Period Type:	duration

- Definition

The maximum number of shares issuable for convertible debt.

+ References

No definition available.

+ Details

Name:	opk_DebtInstrumentConvertibleDebtMaximumSharesIssuable
Namespace Prefix:	opk_
Data Type:	xbrli:sharesItemType
Balance Type:	na
Period Type:	instant

- Definition

The price per share of the conversion feature embedded in the debt instrument.

+ References

+ Details

Name:	us-gaap_DebtInstrumentConvertibleConversionPrice1
Namespace Prefix:	us-gaap_
Data Type:	dtr-types:perShareItemType
Balance Type:	na
Period Type:	instant

- Definition

Ratio applied to the conversion of debt instrument into equity with equity shares divided by debt principal amount.

+ References

Reference 1: http://www.xbrl.org/2003/role/disclosureRef
-Topic 470
-SubTopic 20
-Name Accounting Standards Codification
-Section 50
-Paragraph 1B
-Subparagraph (c)
-Publisher FASB
-URI https://asc.fasb.org//1943274/2147481139/470-20-50-1B

Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef
-Name Accounting Standards Codification
-Topic 505
-SubTopic 10
-Section 50
-Paragraph 3
-Publisher FASB
-URI https://asc.fasb.org//1943274/2147481112/505-10-50-3

Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef
-Name Accounting Standards Codification
-Topic 210
-SubTopic 10
-Section S99
-Paragraph 1
-Subparagraph (SX 210.5-02.22(a)(5))
-Publisher FASB
-URI https://asc.fasb.org//1943274/2147480566/210-10-S99-1

Reference 4: http://fasb.org/us-gaap/role/ref/legacyRef
-Topic 505
-SubTopic 10
-Name Accounting Standards Codification
-Section 50
-Paragraph 7
-Publisher FASB
-URI https://asc.fasb.org//1943274/2147481112/505-10-50-7

Reference 5: http://fasb.org/us-gaap/role/ref/legacyRef
-Topic 505
-SubTopic 10
-Name Accounting Standards Codification
-Section 50
-Paragraph 6
-Subparagraph (b)
-Publisher FASB
-URI https://asc.fasb.org//1943274/2147481112/505-10-50-6

+ Details

Name:	us-gaap_DebtInstrumentConvertibleConversionRatio1
Namespace Prefix:	us-gaap_
Data Type:	xbrli:pureItemType
Balance Type:	na
Period Type:	duration

- Definition

Threshold period of specified consecutive trading days within which common stock price to conversion price of convertible debt instrument must exceed threshold percentage for specified number of trading days to trigger conversion feature.

+ References

No definition available.

+ Details

Name:	us-gaap_DebtInstrumentConvertibleThresholdConsecutiveTradingDays1
Namespace Prefix:	us-gaap_
Data Type:	xbrli:integerItemType
Balance Type:	na
Period Type:	duration

- Definition

Minimum percentage of common stock price to conversion price of convertible debt instruments to determine eligibility of conversion.

+ References

No definition available.

+ Details

Name:	us-gaap_DebtInstrumentConvertibleThresholdPercentageOfStockPriceTrigger
Namespace Prefix:	us-gaap_
Data Type:	dtr-types:percentItemType
Balance Type:	na
Period Type:	duration

- Definition

Threshold number of specified trading days that common stock price to conversion price of convertible debt instruments must exceed threshold percentage within a specified consecutive trading period to trigger conversion feature.

+ References

No definition available.

+ Details

Name:	us-gaap_DebtInstrumentConvertibleThresholdTradingDays
Namespace Prefix:	us-gaap_
Data Type:	xbrli:integerItemType
Balance Type:	na
Period Type:	duration

- Definition

Face (par) amount of debt instrument at time of issuance.

+ References

Reference 1: http://www.xbrl.org/2003/role/disclosureRef
-Topic 835
-SubTopic 30
-Name Accounting Standards Codification
-Section 50
-Paragraph 1
-Publisher FASB
-URI https://asc.fasb.org//1943274/2147482900/835-30-50-1

Reference 2: http://www.xbrl.org/2003/role/disclosureRef
-Topic 470
-SubTopic 20
-Name Accounting Standards Codification
-Section 50
-Paragraph 1B
-Subparagraph (a)
-Publisher FASB
-URI https://asc.fasb.org//1943274/2147481139/470-20-50-1B

Reference 3: http://www.xbrl.org/2003/role/exampleRef
-Topic 470
-SubTopic 20
-Name Accounting Standards Codification
-Section 55
-Paragraph 69B
-Publisher FASB
-URI https://asc.fasb.org//1943274/2147481568/470-20-55-69B

Reference 4: http://www.xbrl.org/2003/role/exampleRef
-Topic 470
-SubTopic 20
-Name Accounting Standards Codification
-Section 55
-Paragraph 69C
-Publisher FASB
-URI https://asc.fasb.org//1943274/2147481568/470-20-55-69C

Reference 5: http://fasb.org/us-gaap/role/ref/legacyRef
-Name Accounting Standards Codification
-Topic 835
-SubTopic 30
-Section 45
-Paragraph 2
-Publisher FASB
-URI https://asc.fasb.org//1943274/2147482925/835-30-45-2

Reference 6: http://fasb.org/us-gaap/role/ref/legacyRef
-Name Accounting Standards Codification
-Topic 835
-SubTopic 30
-Section 55
-Paragraph 8
-Publisher FASB
-URI https://asc.fasb.org//1943274/2147482949/835-30-55-8

+ Details

Name:	us-gaap_DebtInstrumentFaceAmount
Namespace Prefix:	us-gaap_
Data Type:	xbrli:monetaryItemType
Balance Type:	credit
Period Type:	instant

- Definition

Contractual interest rate for funds borrowed, under the debt agreement.

+ References

Reference 1: http://www.xbrl.org/2003/role/disclosureRef
-Topic 470
-SubTopic 20
-Name Accounting Standards Codification
-Section 50
-Paragraph 1B
-Subparagraph (b)
-Publisher FASB
-URI https://asc.fasb.org//1943274/2147481139/470-20-50-1B

Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef
-Name Accounting Standards Codification
-Topic 210
-SubTopic 10
-Section S99
-Paragraph 1
-Subparagraph (SX 210.5-02.22(a)(1))
-Publisher FASB
-URI https://asc.fasb.org//1943274/2147480566/210-10-S99-1

+ Details

Name:	us-gaap_DebtInstrumentInterestRateStatedPercentage
Namespace Prefix:	us-gaap_
Data Type:	dtr-types:percentItemType
Balance Type:	na
Period Type:	instant

- Definition

Percentage price of original principal amount of debt at which debt can be redeemed by the issuer.

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Name Accounting Standards Codification
-Section 50
-Paragraph 3
-Subparagraph e
-SubTopic 470
-Topic 942
-Publisher FASB
-URI https://asc.fasb.org//1943274/2147480848/942-470-50-3

+ Details

Name:	us-gaap_DebtInstrumentRedemptionPricePercentage
Namespace Prefix:	us-gaap_
Data Type:	dtr-types:percentItemType
Balance Type:	na
Period Type:	duration

- Definition

Fair value amount of debt instrument that was repurchased.

+ References

No definition available.

+ Details

Name:	us-gaap_DebtInstrumentRepurchaseAmount
Namespace Prefix:	us-gaap_
Data Type:	xbrli:monetaryItemType
Balance Type:	debit
Period Type:	instant

- Definition

Amount of interest payable on debt, including, but not limited to, trade payables.

+ References

Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
-Topic 944
-SubTopic 210
-Name Accounting Standards Codification
-Section S99
-Paragraph 1
-Subparagraph (SX 210.7-03(a)(15)(a))
-Publisher FASB
-URI https://asc.fasb.org//1943274/2147479440/944-210-S99-1

Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef
-Name Accounting Standards Codification
-Topic 942
-SubTopic 210
-Section S99
-Paragraph 1
-Subparagraph (SX 210.9-03.15(5))
-Publisher FASB
-URI https://asc.fasb.org//1943274/2147479853/942-210-S99-1

+ Details

Name:	us-gaap_InterestPayableCurrentAndNoncurrent
Namespace Prefix:	us-gaap_
Data Type:	xbrli:monetaryItemType
Balance Type:	credit
Period Type:	instant

- Definition

Amount, after deduction of unamortized premium (discount) and debt issuance cost, of long-term debt. Excludes lease obligation.

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Name Accounting Standards Codification
-Section S99
-Paragraph 1
-Subparagraph (SX 210.5-02(22))
-SubTopic 10
-Topic 210
-Publisher FASB
-URI https://asc.fasb.org//1943274/2147480566/210-10-S99-1

Reference 2: http://www.xbrl.org/2003/role/exampleRef
-Topic 470
-SubTopic 20
-Name Accounting Standards Codification
-Section 55
-Paragraph 69B
-Publisher FASB
-URI https://asc.fasb.org//1943274/2147481568/470-20-55-69B

Reference 3: http://www.xbrl.org/2003/role/exampleRef
-Topic 470
-SubTopic 20
-Name Accounting Standards Codification
-Section 55
-Paragraph 69C
-Publisher FASB
-URI https://asc.fasb.org//1943274/2147481568/470-20-55-69C

Reference 4: http://www.xbrl.org/2003/role/disclosureRef
-Topic 470
-SubTopic 20
-Name Accounting Standards Codification
-Section 50
-Paragraph 1D
-Subparagraph (b)
-Publisher FASB
-URI https://asc.fasb.org//1943274/2147481139/470-20-50-1D

Reference 5: http://www.xbrl.org/2009/role/commonPracticeRef
-Topic 944
-SubTopic 210
-Name Accounting Standards Codification
-Section S99
-Paragraph 1
-Subparagraph (SX 210.7-03(a)(16)(a)(2))
-Publisher FASB
-URI https://asc.fasb.org//1943274/2147479440/944-210-S99-1

Reference 6: http://fasb.org/us-gaap/role/ref/legacyRef
-Topic 942
-SubTopic 210
-Name Accounting Standards Codification
-Section S99
-Paragraph 1
-Subparagraph (SX 210.9-03(16))
-Publisher FASB
-URI https://asc.fasb.org//1943274/2147479853/942-210-S99-1

Reference 7: http://www.xbrl.org/2003/role/disclosureRef
-Topic 470
-SubTopic 20
-Name Accounting Standards Codification
-Section 50
-Paragraph 4
-Subparagraph (b)(3)
-Publisher FASB
-URI https://asc.fasb.org//1943274/2147481139/470-20-50-4

+ Details

Name:	us-gaap_LongTermDebt
Namespace Prefix:	us-gaap_
Data Type:	xbrli:monetaryItemType
Balance Type:	credit
Period Type:	instant

- Definition

The cash outflow to reacquire common stock during the period.

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Name Accounting Standards Codification
-Topic 230
-SubTopic 10
-Section 45
-Paragraph 15
-Subparagraph (a)
-Publisher FASB
-URI https://asc.fasb.org//1943274/2147482740/230-10-45-15

+ Details

Name:	us-gaap_PaymentsForRepurchaseOfCommonStock
Namespace Prefix:	us-gaap_
Data Type:	xbrli:monetaryItemType
Balance Type:	credit
Period Type:	duration

- Definition

The cash inflow during the period from additional borrowings in aggregate debt. Includes proceeds from short-term and long-term debt.

+ References

Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
-Topic 230
-SubTopic 10
-Name Accounting Standards Codification
-Section 45
-Paragraph 14
-Subparagraph (b)
-Publisher FASB
-URI https://asc.fasb.org//1943274/2147482740/230-10-45-14

+ Details

Name:	us-gaap_ProceedsFromIssuanceOfDebt
Namespace Prefix:	us-gaap_
Data Type:	xbrli:monetaryItemType
Balance Type:	debit
Period Type:	duration

- Definition

Price of a single share of a number of saleable stocks of a company.

+ References

No definition available.

+ Details

Name:	us-gaap_SharePrice
Namespace Prefix:	us-gaap_
Data Type:	dtr-types:perShareItemType
Balance Type:	na
Period Type:	instant

- Details

Name:	us-gaap_DebtInstrumentAxis=opk_Th2029ConvertibleNotesMember
Namespace Prefix:
Data Type:	na
Balance Type:
Period Type:

- Details

Name:	us-gaap_LongtermDebtTypeAxis=us-gaap_ConvertibleDebtMember
Namespace Prefix:
Data Type:	na
Balance Type:
Period Type:

- Details

Name:	us-gaap_SubsequentEventTypeAxis=us-gaap_SubsequentEventMember
Namespace Prefix:
Data Type:	na
Balance Type:
Period Type:

- Details

Name:	us-gaap_DebtInstrumentRedemptionPeriodAxis=us-gaap_DebtInstrumentRedemptionPeriodOneMember
Namespace Prefix:
Data Type:	na
Balance Type:
Period Type:

- Details

Name:	us-gaap_DebtInstrumentRedemptionPeriodAxis=us-gaap_DebtInstrumentRedemptionPeriodTwoMember
Namespace Prefix:
Data Type:	na
Balance Type:
Period Type:

- Details

Name:	us-gaap_DebtInstrumentAxis=opk_The2025NotesMember
Namespace Prefix:
Data Type:	na
Balance Type:
Period Type:

- Details

Name:	us-gaap_DebtInstrumentAxis=opk_The2023ConvertibleNotesMember
Namespace Prefix:
Data Type:	na
Balance Type:
Period Type:

- Details

Name:	us-gaap_DebtInstrumentAxis=opk_ConvertibleSeniorNotesDue2025Member
Namespace Prefix:
Data Type:	na
Balance Type:
Period Type:

Note 22 - Subsequent Events (Details Textual) $ / shares in Units, $ in Thousands				1 Months Ended
	Jan. 31, 2024 USD ($) $ / shares	Jan. 22, 2024 USD ($) shares	Jan. 09, 2024 USD ($)	Jan. 31, 2024 USD ($) $ / shares	May 31, 2021 shares	Feb. 28, 2019 USD ($) $ / shares shares	Jan. 04, 2024 USD ($) $ / shares	Dec. 31, 2023 USD ($)	Dec. 31, 2022 USD ($)	Feb. 28, 2018 USD ($) $ / shares
Long-Term Debt								$ 249,345	$ 256,251
The 2029 Convertible Notes [Member] \| Convertible Debt [Member] \| Subsequent Event [Member]
Debt Instrument, Face Amount	$ 230,000			$ 230,000			$ 71,100
Debt Instrument, Interest Rate, Stated Percentage	3.75%			3.75%
Debt Instrument, Aggregate Principle Amount Purchased on Closing Date				$ 30,000
Proceeds from Issuance of Debt	$ 222,000,000		$ 146,300
Payments for Repurchase of Common Stock	$ 50,000
Share Price (in dollars per share) \| $ / shares							$ 0.9067
Cash Used or Repurchase of Notes							$ 146,300
Debt Instrument, Convertible, Conversion Ratio				869.5652
Debt Instrument, Convertible, Conversion Price (in dollars per share) \| $ / shares	$ 1.15			$ 1.15
The 2029 Convertible Notes [Member] \| Convertible Debt [Member] \| Subsequent Event [Member] \| Debt Instrument, Redemption, Period One [Member]
Debt Instrument, Convertible, Threshold Trading Days				20
Debt Instrument, Convertible, Threshold Consecutive Trading Days				30
Debt Instrument, Convertible, Threshold Percentage of Stock Price Trigger				130.00%
Debt Instrument, Redemption Price, Percentage				100.00%
The 2029 Convertible Notes [Member] \| Convertible Debt [Member] \| Subsequent Event [Member] \| Debt Instrument, Redemption, Period Two [Member]
Debt Instrument, Convertible, Threshold Percentage of Stock Price Trigger				98.00%
The 2025 Notes [Member]
Long-Term Debt								143,250	142,096
The 2025 Notes [Member] \| Convertible Debt [Member]
Debt Instrument, Face Amount						$ 200,000
Debt Instrument, Interest Rate, Stated Percentage						4.50%
Debt Instrument, Convertible, Conversion Ratio						236.7424
Debt Instrument, Convertible, Conversion Price (in dollars per share) \| $ / shares						$ 4.22
Debt Instrument, Convertible Debt, Maximum Shares Issuable (in shares) \| shares						30,000,000
Debt Instrument, Convertible Debt, Increase (Decrease) in Maximum Shares Issuable (in shares) \| shares					8,105,175
The 2025 Notes [Member] \| Convertible Debt [Member] \| Debt Instrument, Redemption, Period One [Member]
Debt Instrument, Convertible, Threshold Trading Days						20
Debt Instrument, Convertible, Threshold Consecutive Trading Days						30
Debt Instrument, Convertible, Threshold Percentage of Stock Price Trigger						130.00%
Debt Instrument, Redemption Price, Percentage						100.00%
The 2025 Notes [Member] \| Convertible Debt [Member] \| Debt Instrument, Redemption, Period Two [Member]
Debt Instrument, Convertible, Threshold Trading Days						5
Debt Instrument, Convertible, Threshold Consecutive Trading Days						5
Debt Instrument, Convertible, Threshold Percentage of Stock Price Trigger						98.00%
The 2025 Notes [Member] \| Convertible Debt [Member] \| Subsequent Event [Member]
Debt Instrument, Face Amount			170
Debt Instrument, Repurchase Amount			144,400				144,400
The 2023 Convertible Notes [Member]
Long-Term Debt								$ 71,025	$ 68,275
The 2023 Convertible Notes [Member] \| Convertible Debt [Member]
Debt Instrument, Face Amount										$ 55,000
Debt Instrument, Interest Rate, Stated Percentage										5.00%
Debt Instrument, Convertible, Conversion Price (in dollars per share) \| $ / shares										$ 5
The 2023 Convertible Notes [Member] \| Convertible Debt [Member] \| Subsequent Event [Member]
Debt Instrument, Face Amount			55,000				55,000
Interest Payable			$ 16,100				16,100
Long-Term Debt							$ 0
Convertible Senior Notes Due 2025 [Member] \| Convertible Debt [Member] \| Subsequent Event [Member]
Debt Instrument, Face Amount		$ 200,000
Debt Instrument, Convertible Debt, Maximum Shares Issuable (in shares) \| shares		30,000,000
Debt Instrument, Convertible Debt, Increase (Decrease) in Maximum Shares Issuable (in shares) \| shares		8,313,000