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Note 14 - Commitments and Contingencies (Details Textual) - USD ($)
12 Months Ended
Dec. 29, 2022
Jul. 14, 2022
May 26, 2022
Dec. 31, 2023
Dec. 31, 2022
Dec. 31, 2021
Business Combination, Contingent Consideration, Liability         $ 1,000,000 $ 2,800,000
Purchase Obligation       $ 34,700,000    
Settled Litigation [Member]            
Litigation Settlement, Amount Awarded to Other Party   $ 10,000,000        
Litigation Settlement, Interest Rate   1.50%        
Settled Litigation [Member] | UNITED STATES            
Litigation Settlement, Amount Awarded to Other Party   $ 9,853,958        
Settled Litigation [Member] | Commonwealth [Member]            
Litigation Settlement, Amount Awarded to Other Party   141,041        
Settled Litigation [Member] | CONNECTICUT            
Litigation Settlement, Amount Awarded to Other Party   $ 5,001        
Threatened Litigation [Member] | Texas Medicaid Office [Member]            
Litigation Settlement, Amount Awarded to Other Party     $ 231,000      
CURNA, OPKO Diagnostics and OPKO Renal [Member]            
Business Combination, Contingent Consideration, Liability       0 $ 1,000,000  
Israel Tax Authority [Member]            
Income Tax Examination, Estimate of Possible Loss       $ 246,000,000    
Foreign Tax Authority [Member] | Israel Tax Authority [Member] | Tax Year 2014 Through Tax Year 2020 [Member]            
Income Tax Examination, Estimate of Possible Loss $ 246,000,000