Note 11 - Income Taxes - Reconciliation of Effective Income Tax Rate (Details)			12 Months Ended
	Jan. 01, 2018	Dec. 22, 2017	Dec. 31, 2023	Dec. 31, 2022	Dec. 31, 2021
Federal statutory rate	21.00%	35.00%	21.00%	21.00%	21.00%
State income taxes, net of federal benefit			4.70%	4.00%	(7.90%)
Foreign income tax			(2.50%)	(2.00%)	21.60%
Income Tax Refunds			(0.40%)	0.00%	6.10%
Research and development tax credits			0.70%	0.20%	2.30%
GeneDx Disposition			0.00%	0.80%	0.00%
Valuation allowance			(7.00%)	(6.30%)	235.40%
Rate change effect			0.40%	5.20%	(40.50%)
Non-deductible items			(0.60%)	0.60%	(67.00%)
Unrecognized tax benefits			0.70%	(0.70%)	11.30%
GILTI			(14.80%)	(4.90%)	0.00%
Stock options excess tax benefit, cancellations & expirations			(2.30%)	(0.30%)	(3.80%)
Imputed interest			(0.80%)	(0.40%)	(6.30%)
Investment in subsidiaries			0.00%	0.00%	(287.60%)
Tax on deemed dividend			0.00%	(1.00%)	0.00%
True-Up to Adjustments			(2.30%)	0.00%	0.00%
Other			0.80%	0.00%	9.70%
Total			(2.40%)	16.20%	(105.70%)