Note 7 - Debt (Details Textual)			1 Months Ended				12 Months Ended			47 Months Ended
	Jan. 31, 2024 USD ($) $ / shares	Jan. 09, 2024 USD ($)	Jan. 31, 2024 USD ($) $ / shares	May 31, 2021 USD ($) shares	Feb. 28, 2019 USD ($) $ / shares shares	Feb. 28, 2018 USD ($) $ / shares	Dec. 31, 2023 USD ($) shares	Dec. 31, 2022 USD ($) shares	Dec. 31, 2021 USD ($)	Dec. 31, 2016 USD ($)	Jan. 04, 2024 USD ($)	Jun. 29, 2023 USD ($)	Jan. 31, 2023 USD ($)	Jan. 01, 2022 USD ($)	Dec. 31, 2020 USD ($)	Feb. 01, 2019 USD ($)	Nov. 30, 2015 USD ($)	Jan. 31, 2013
Gain (Loss) on Conversion of Debt							$ (0)	$ (0)	$ (11,111,000)
Retained Earnings (Accumulated Deficit)							(2,011,786,000)	(1,822,923,000)
Additional Paid in Capital							3,433,006,000	3,421,872,000
Debt Conversion, Converted Instrument, Amount							0	0	68,775,000
Long-Term Debt							249,345,000	256,251,000
Line of Credit Facility, Maximum Borrowing Capacity							80,367,000
Equity, Attributable to Parent							1,389,219,000	1,561,648,000	1,685,126,000						$ 1,671,551,000
Goodwill							598,260,000	595,851,000
Intangible Assets, Net (Excluding Goodwill)							$ 740,283,000	823,520,000
Minimum [Member]
Long-Term Debt, Percentage Bearing Variable Interest, Percentage Rate							0.70%
Maximum [Member]
Long-Term Debt, Percentage Bearing Variable Interest, Percentage Rate							5.10%
BioReference [Member]
Equity, Attributable to Parent							$ 488,300,000
Goodwill							283,000,000
Intangible Assets, Net (Excluding Goodwill)							167,800,000
Accounting Standards Update 2020-06 [Member] | Cumulative Effect, Period of Adoption, Adjustment [Member]
Retained Earnings (Accumulated Deficit)														$ (17,500,000)
Additional Paid in Capital														(39,100,000)
Conversion of the 2025 Notes into Common Stock [Member]
Debt Conversion, Original Debt, Amount				$ 55,400,000
Debt Conversion, Converted Instrument, Shares Issued (in shares) | shares				19,051,270
Gain (Loss) on Conversion of Debt									$ 11,100,000
Senior Notes [Member]
Long-Term Debt							$ 143,250,000	$ 142,096,000
Line of Credit [Member]
Debt, Weighted Average Interest Rate							7.52%	5.50%
The 2025 Notes [Member]
Long-Term Debt							$ 143,250,000	$ 142,096,000
The 2025 Notes [Member] | Accounting Standards Update 2020-06 [Member] | Cumulative Effect, Period of Adoption, Adjustment [Member]
Convertible Debt														$ 21,600,000
The 2025 Notes [Member] | Convertible Debt [Member]
Debt Instrument, Face Amount					$ 200,000,000
Debt Instrument, Interest Rate, Stated Percentage					4.50%
Debt Instrument, Convertible, Conversion Ratio					236.7424
Debt Instrument, Convertible, Conversion Price (in dollars per share) | $ / shares					$ 4.22
Debt Instrument, Convertible Debt, Maximum Shares Issuable (in shares) | shares					30,000,000
Debt Instrument, Convertible Debt, Increase (Decrease) in Maximum Shares Issuable (in shares) | shares				8,105,175
Debt Conversion, Converted Instrument, Shares Outstanding (in shares) | shares							21,144,825	21,144,825
Proceeds From Convertible Debt, Conversion Fee					$ 300,000
The 2025 Notes [Member] | Convertible Debt [Member] | Subsequent Event [Member]
Debt Instrument, Face Amount		$ 170,000
Debt Instrument, Repurchase Amount		144,400,000									$ 144,400,000
The 2025 Notes [Member] | Convertible Debt [Member] | Debt Instrument, Redemption, Period One [Member]
Debt Instrument, Convertible, Threshold Trading Days					20
Debt Instrument, Convertible, Threshold Consecutive Trading Days					30
Debt Instrument, Convertible, Threshold Percentage of Stock Price Trigger					130.00%
Debt Instrument, Redemption Price, Percentage					100.00%
The 2025 Notes [Member] | Convertible Debt [Member] | Debt Instrument, Redemption, Period Two [Member]
Debt Instrument, Convertible, Threshold Trading Days					5
Debt Instrument, Convertible, Threshold Consecutive Trading Days					5
Debt Instrument, Convertible, Threshold Percentage of Stock Price Trigger					98.00%
The 2025 Notes [Member] | Convertible Debt [Member] | Debt Instrument, Redemption, Period Three [Member]
Debt Instrument, Convertible, Threshold Trading Days					20
Debt Instrument, Convertible, Threshold Consecutive Trading Days					30
Debt Instrument, Convertible, Threshold Percentage of Stock Price Trigger					130.00%
Debt Instrument, Redemption Price, Percentage					100.00%
The 2029 Convertible Notes [Member] | Convertible Debt [Member] | Subsequent Event [Member]
Debt Instrument, Face Amount	$ 230,000,000		$ 230,000,000								71,100,000
Debt Instrument, Interest Rate, Stated Percentage	3.75%		3.75%
Debt Instrument, Convertible, Conversion Ratio			869.5652
Debt Instrument, Convertible, Conversion Price (in dollars per share) | $ / shares	$ 1.15		$ 1.15
Proceeds from Issuance of Debt	$ 222,000,000,000	146,300,000
Debt Instrument, Issued, Principal		71,100,000
The 2029 Convertible Notes [Member] | Convertible Debt [Member] | Debt Instrument, Redemption, Period One [Member] | Subsequent Event [Member]
Debt Instrument, Convertible, Threshold Trading Days			20
Debt Instrument, Convertible, Threshold Consecutive Trading Days			30
Debt Instrument, Convertible, Threshold Percentage of Stock Price Trigger			130.00%
Debt Instrument, Redemption Price, Percentage			100.00%
The 2029 Convertible Notes [Member] | Convertible Debt [Member] | Debt Instrument, Redemption, Period Two [Member] | Subsequent Event [Member]
Debt Instrument, Convertible, Threshold Percentage of Stock Price Trigger			98.00%
The 2023 Convertible Notes [Member]
Long-Term Debt							$ 71,025,000	$ 68,275,000
The 2023 Convertible Notes [Member] | Convertible Debt [Member]
Debt Instrument, Face Amount						$ 55,000,000
Debt Instrument, Interest Rate, Stated Percentage						5.00%
Debt Instrument, Convertible, Conversion Price (in dollars per share) | $ / shares						$ 5
Debt Instrument, Term (Year)						5 years
Debt Instrument, Convertible, Conversion Premium, Percent						25.00%
Debt Instrument, Convertible, Conversion Premium, Per Share (in dollars per share) | $ / shares						$ 1.66
The 2023 Convertible Notes [Member] | Convertible Debt [Member] | Subsequent Event [Member]
Debt Instrument, Face Amount		55,000,000									55,000,000
Interest Payable		16,100,000									16,100,000
Long-Term Debt											$ 0
The 2029 Notes [Member] | Convertible Debt [Member] | Subsequent Event [Member]
Debt Instrument, Issued, Principal		$ 71,100,000
The 2033 Senior Notes [Member]
Long-Term Debt							50,000	3,050,000
The 2033 Senior Notes [Member] | Convertible Debt [Member]
Debt Instrument, Repurchase Amount																$ 28,800,000
Debt Conversion, Converted Instrument, Amount										$ 143,200,000
Repayments of Debt							3,000,000
Long-Term Debt							50,600
The 2033 Senior Notes [Member] | Senior Notes [Member]
Debt Instrument, Face Amount													$ 175,000,000
Debt Instrument, Interest Rate, Stated Percentage																		3.00%
Credit Agreement [Member] | Line of Credit [Member] | Revolving Credit Facility [Member]
Line of Credit Facility, Maximum Borrowing Capacity												$ 50,000,000					$ 75,000,000
Line of Credit Facility, Remaining Borrowing Capacity							$ 7,500,000
Line of Credit Facility, Unused Capacity, Commitment Fee Percentage							0.40%
Long-Term Line of Credit, Noncurrent							$ 12,700,000	$ 18,100,000
Credit Agreement [Member] | Line of Credit [Member] | Revolving Credit Facility [Member] | Quarterly Availability is 50% or More [Member]
Line of Credit Facility, Commitment Fee Percentage							1.00%
Line of Credit Facility, Unused Capacity, Commitment Fee Percentage							0.275%
Credit Agreement [Member] | Line of Credit [Member] | Revolving Credit Facility [Member] | London Interbank Offered Rate [Member]
Debt Instrument, Basis Spread on Variable Rate							2.50%
Credit Agreement [Member] | Line of Credit [Member] | Revolving Credit Facility [Member] | Secured Overnight Financing Rate 12 Months [Member] | Quarterly Availability is 50% or More [Member]
Debt Instrument, Basis Spread on Variable Rate							0.10%
Credit Agreement [Member] | Line of Credit [Member] | Revolving Credit Facility [Member] | Secured Overnight Financing Rate (SOFR) Overnight Index Swap Rate [Member]
Debt Instrument, Basis Spread on Variable Rate							2.00%
Debt Instrument, Basis Spread on Variable Rate, Benchmark Adjustment							0.10%
Credit Agreement [Member] | Line of Credit [Member] | Bridge Loan [Member]
Line of Credit Facility, Maximum Borrowing Capacity																	20,000,000
Credit Agreement [Member] | Line of Credit [Member] | Letter of Credit [Member]
Line of Credit Facility, Maximum Borrowing Capacity																	$ 20,000,000
Notes and Other Debt [Member]
Debt, Weighted Average Interest Rate							2.90%	3.50%