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Schedule I - Parent Company Condensed Statements of Cash Flows (Details) - USD ($)
$ in Thousands
3 Months Ended 12 Months Ended
Dec. 31, 2023
Sep. 30, 2023
Jun. 30, 2023
Mar. 31, 2023
Dec. 31, 2022
Sep. 30, 2022
Jun. 30, 2022
Mar. 31, 2022
Dec. 31, 2023
Dec. 31, 2022
Dec. 31, 2021
Net loss $ (66,483) $ (84,473) $ (19,640) $ (18,267) $ (85,231) $ (86,091) $ (101,650) $ (55,433) $ (188,863) $ (328,405) $ (30,143)
Adjustments to reconcile net loss to net cash used in operating activities:                      
Non-cash interest                 2,750 2,750 9,389
Amortization of debt discount and debt issuance costs                 1,222 1,161 785
Losses from investments in investees                 107 383 629
Share-Based Payment Arrangement, Noncash Expense                 11,413 18,509 13,632
Non-cash revenue from the transfer of intellectual property                 0 0 (3,801)
Realized gain on equity securities and disposal of fixed assets                 1,321 (455) (33,922)
Loss on conversion of the 2025 Notes                 0 0 11,111
Gain on sale of GeneDx                 0 (18,559) 0
Net cash (used in) provided by operating activities                 (28,197) (95,189) 38,337
Cash flows from investing activities:                      
Investments in investees                 (5,000) 0 (2,000)
Net cash (used in) provided by investing activities                 (18,198) 91,038 35,949
Cash flows from financing activities:                      
Redemption of 2033 Senior Notes                 (3,000) 0 0
Net cash (used in) provided by financing activities                 (11,303) 22,971 (10,350)
Net increase (decrease) in cash and cash equivalents                 (57,310) 18,481 62,499
Cash and cash equivalents at beginning of period       153,191       134,710 153,191 134,710 72,211
Cash and cash equivalents at end of period 95,881       153,191       95,881 153,191 134,710
SUPPLEMENTAL INFORMATION:                      
Interest paid                 8,135 7,420 8,515
Income taxes paid, net of refunds                 3,712 8,037 5,969
Parent Company [Member]                      
Net loss                 (188,863) (328,405) (30,143)
Adjustments to reconcile net loss to net cash used in operating activities:                      
Non-cash interest                 2,750 2,750 9,389
Amortization of debt discount and debt issuance costs                 1,154 1,093 722
Losses from investments in investees                 107 383 629
(Income) loss from subsidiaries                 110,953 126,425 (70,313)
Share-Based Payment Arrangement, Noncash Expense                 11,414 18,509 13,632
Non-cash revenue from the transfer of intellectual property                 0 0 (3,801)
Realized gain on equity securities and disposal of fixed assets                 (364) 0 (2,981)
Change in fair value of derivative instruments and equity securities                 16,891 154,473 4,871
Loss on conversion of the 2025 Notes                 0 0 11,111
Gain on sale of GeneDx                 0 (18,559) 0
Changes in other assets and liabilities                 11,559 (14,993) 10,970
Net cash (used in) provided by operating activities                 (34,399) (58,324) (55,914)
Cash flows from investing activities:                      
Investments in investees                 (5,000) 0 (2,000)
Subsidiary financing                 (30,242) 23,866 69,608
Proceeds from sale of investments                 364 0 0
Proceeds from sale of equity securities                 0 115,423 8,078
Net cash (used in) provided by investing activities                 (34,878) 139,289 75,686
Cash flows from financing activities:                      
Proceeds from the exercise of Common Stock options and warrants                 (272) (774) 1,080
Redemption of 2033 Senior Notes                 (3,000) 0 0
Net cash (used in) provided by financing activities                 (3,272) (774) 1,080
Net increase (decrease) in cash and cash equivalents                 (72,549) 80,191 20,852
Cash and cash equivalents at beginning of period       $ 104,783       $ 24,592 104,783 24,592 3,740
Cash and cash equivalents at end of period 32,234       104,783       32,234 104,783 24,592
SUPPLEMENTAL INFORMATION:                      
Interest paid                 8,135 7,420 8,515
Income taxes paid, net of refunds                 3,712 8,037 5,969
Non-cash financing:                      
Common Stock options and warrants, surrendered in net exercise $ 301       $ 1,268       301 1,268 0
Issuance of common stock for acquisition of ModeX                 0 221,662 0
Business Combination, Consideration Transferred, Equity Interests Issued and Issuable                 $ 6,689 $ 172,000 $ 0