0001209191-16-139955.txt : 20160906 0001209191-16-139955.hdr.sgml : 20160906 20160906110036 ACCESSION NUMBER: 0001209191-16-139955 CONFORMED SUBMISSION TYPE: 4 PUBLIC DOCUMENT COUNT: 2 CONFORMED PERIOD OF REPORT: 20160902 FILED AS OF DATE: 20160906 DATE AS OF CHANGE: 20160906 ISSUER: COMPANY DATA: COMPANY CONFORMED NAME: Opko Health, Inc. CENTRAL INDEX KEY: 0000944809 STANDARD INDUSTRIAL CLASSIFICATION: PHARMACEUTICAL PREPARATIONS [2834] IRS NUMBER: 752402409 STATE OF INCORPORATION: DE FISCAL YEAR END: 1231 BUSINESS ADDRESS: STREET 1: 4400 BISCAYNE BLVD. CITY: MIAMI STATE: FL ZIP: 33137 BUSINESS PHONE: 305-575-4138 MAIL ADDRESS: STREET 1: 4400 BISCAYNE BLVD. CITY: MIAMI STATE: FL ZIP: 33137 FORMER COMPANY: FORMER CONFORMED NAME: eXegenics Inc DATE OF NAME CHANGE: 20040505 FORMER COMPANY: FORMER CONFORMED NAME: EXEGENICS INC DATE OF NAME CHANGE: 20011114 FORMER COMPANY: FORMER CONFORMED NAME: CYTOCLONAL PHARMACEUTICS INC /DE DATE OF NAME CHANGE: 19950503 REPORTING-OWNER: OWNER DATA: COMPANY CONFORMED NAME: Frost Gamma Investments Trust CENTRAL INDEX KEY: 0001380896 FILING VALUES: FORM TYPE: 4 SEC ACT: 1934 Act SEC FILE NUMBER: 001-33528 FILM NUMBER: 161870141 BUSINESS ADDRESS: STREET 1: 4400 BISCAYNE BOULEVARD, 15TH FLOOR CITY: MIAMI STATE: FL ZIP: 33137 BUSINESS PHONE: 305-575-6000 MAIL ADDRESS: STREET 1: 4400 BISCAYNE BOULEVARD, 15TH FLOOR CITY: MIAMI STATE: FL ZIP: 33137 FORMER NAME: FORMER CONFORMED NAME: Frost Gamma Investment Trust DATE OF NAME CHANGE: 20061113 REPORTING-OWNER: OWNER DATA: COMPANY CONFORMED NAME: FROST PHILLIP MD ET AL CENTRAL INDEX KEY: 0000898860 FILING VALUES: FORM TYPE: 4 SEC ACT: 1934 Act SEC FILE NUMBER: 001-33528 FILM NUMBER: 161870142 MAIL ADDRESS: STREET 1: 4400 BISCAYNE BLVD CITY: MIAMI STATE: FL ZIP: 33137-3227 4 1 doc4.xml FORM 4 SUBMISSION X0306 4 2016-09-02 0 0000944809 Opko Health, Inc. OPK 0000898860 FROST PHILLIP MD ET AL OPKO HEALTH, INC. 4400 BISCAYNE BLVD. MIAMI FL 33137 1 1 1 0 CEO & Chairman 0001380896 Frost Gamma Investments Trust 4400 BISCAYNE BLVD. MIAMI FL 33137 0 0 1 0 Common Stock 3068951 D Common Stock 2016-09-02 4 P 0 1000 9.18 A 160112543 I See Footnote Common Stock 2016-09-02 4 P 0 1000 9.20 A 160113543 I See Footnote Common Stock 2016-09-02 4 P 0 1000 9.22 A 160114543 I See Footnote Common Stock 2016-09-02 4 P 0 1000 9.26 A 160115543 I See Footnote Common Stock 2016-09-02 4 P 0 1000 9.28 A 160116543 I See Footnote Common Stock 2016-09-02 4 P 0 1000 9.31 A 160117543 I See Footnote Common Stock 2016-09-02 4 P 0 1000 9.33 A 160118543 I See Footnote Common Stock 2016-09-02 4 P 0 3000 9.34 A 160121543 I See Footnote Common Stock 20091062 I See Footnote The securities are held by Frost Gamma Investments Trust, of which Phillip Frost M.D., is the trustee. Frost Gamma L.P. is the sole and exclusive beneficiary of Frost Gamma Investments Trust. Dr. Frost is one of two limited partners of Frost Gamma L.P. The general partner of Frost Gamma L.P. is Frost Gamma, Inc., and the sole shareholder of Frost Gamma, Inc. is Frost-Nevada Corporation. Dr. Frost is also the sole shareholder of Frost-Nevada Corporation. The reporting person disclaims beneficial ownership of these securities, except to the extent of any pecuniary interest therein and this report shall not be deemed an admission that the reporting person is the beneficial owner of these securities for purposes of Section 16 or for any other purpose. These securities are owned directly by The Frost Group, LLC. Frost Gamma Investments Trust is a principal member of The Frost Group, LLC. The reporting person disclaims beneficial ownership of these securities, except to the extent of any pecuniary interest therein and this report shall not be deemed an admission that the reporting person is the beneficial owner of these securities for purposes of Section 16 or for any other purpose. Phillip Frost, M.D., Individually and as Trustee 2016-09-06 EX-99 2 attachment1.htm EX-99 DOCUMENT

JOINT FILER INFORMATION

Name:	Frost Gamma Investments Trust

Address:
4400 Biscayne Blvd.
	Miami, FL  33137

Designated Filer:	Phillip Frost, M.D.

Issuer Name and Ticker Symbol:	OPKO Health, Inc. (OPK)

Date of Earliest Transaction:	September 2, 2016

Relationship to Issuer:	10% Owner


FROST GAMMA INVESTMENTS TRUST

	By:	/s/ Phillip Frost, M.D., as Trustee
	Phillip Frost, M.D., Trustee