Note 6 - Investments (Details Textual) - USD ($) $ in Thousands	1 Months Ended	3 Months Ended		9 Months Ended		12 Months Ended
	Sep. 30, 2021	Sep. 30, 2025	Sep. 30, 2024	Sep. 30, 2025	Sep. 30, 2024	Dec. 31, 2024
Schedule of Equity Method Investments [Line Items]
Proceeds from Sale of Equity Securities, FV-NI				$ 51,655	$ 46,731
Revenue from Contract with Customer, Excluding Assessed Tax		$ 151,669	$ 173,632	458,429	$ 529,504
Assets		1,995,508		1,995,508		$ 2,200,212
Liabilities		690,018		690,018		834,764
Equity Method Investment, Quoted Market Value		300		300		500
Equity Method Investment, Nonconsolidated Investee or Group of Investees [Member]
Schedule of Equity Method Investments [Line Items]
Assets		47,100		47,100		50,900
Liabilities		$ 21,200		21,200		18,300
Net Income (Loss), Including Portion Attributable to Noncontrolling Interest				$ 17,200		$ 31,100
GeneDx Holdings [Member]
Schedule of Equity Method Investments [Line Items]
Investment Owned, Shares Sold (in shares)				620,000
Proceeds from Sale of Equity Securities, FV-NI				$ 51,700
Investment Owned, Balance, Shares (in shares)		0		0
Equity Method Investment, Ownership Percentage						2.20%
Entera Bio Ltd. [Member]
Schedule of Equity Method Investments [Line Items]
Equity Security, FV-NI, Ownership Percent		8.10%		8.10%
ChromaDex Corporation [Member]
Schedule of Equity Method Investments [Line Items]
Equity Security, FV-NI, Ownership Percent		0.04%		0.04%
Eloxx Pharmaceuticals, Inc. [Member]
Schedule of Equity Method Investments [Line Items]
Equity Security, FV-NI, Ownership Percent		1.00%		1.00%
Xenetic Biosciences, Inc. [Member]
Schedule of Equity Method Investments [Line Items]
Equity Security, FV-NI, Ownership Percent		3.00%		3.00%
CAMP4 Therapeutics Corporation [Member]
Schedule of Equity Method Investments [Line Items]
Equity Security, FV-NI, Ownership Percent		1.00%		1.00%
HealthSnap, Inc. [Member]
Schedule of Equity Method Investments [Line Items]
Equity Security, FV-NI, Ownership Percent		4.00%		4.00%
Zebra [Member]
Schedule of Equity Method Investments [Line Items]
Equity Method Investment, Ownership Percentage		29.00%		29.00%
Zebra [Member] | Variable Interest Entity, Not Primary Beneficiary [Member] | Series A-2 Preferred Stock [Member]
Schedule of Equity Method Investments [Line Items]
Investment Owned, Balance, Shares (in shares)		1,260,000		1,260,000		1,260,000
Zebra [Member] | Variable Interest Entity, Not Primary Beneficiary [Member] | Restricted Stock [Member]
Schedule of Equity Method Investments [Line Items]
Investment Owned, Balance, Shares (in shares)		900,000		900,000		900,000
Equity Method Investment, Ownership Percentage		29.00%		29.00%		29.00%
BioCardia [Member]
Schedule of Equity Method Investments [Line Items]
Equity Method Investment, Ownership Percentage		0.26%		0.26%
Class of Warrant or Right, Number of Securities Called by Warrants or Rights (in shares)		47,000		47,000		47,000
Pharmsynthez [Member]
Schedule of Equity Method Investments [Line Items]
Equity Method Investment, Ownership Percentage		6.00%		6.00%
COCP [Member]
Schedule of Equity Method Investments [Line Items]
Equity Method Investment, Ownership Percentage		2.00%		2.00%
NIMS [Member]
Schedule of Equity Method Investments [Line Items]
Equity Method Investment, Ownership Percentage		1.00%		1.00%
LeaderMed [Member]
Schedule of Equity Method Investments [Line Items]
Equity Method Investment, Ownership Percentage		47.00%		47.00%
LeaderMed [Member] | LeaderMed Joint Venture [Member]
Schedule of Equity Method Investments [Line Items]
Minority Interest, Shares Issued (in shares)	4,703
Subsidiary, Ownership Percentage, Parent	47.00%
Revenue from Contract with Customer, Excluding Assessed Tax	$ 1,000